Publications by authors named "Dafina Fondaj"
Article Synopsis
- This study focuses on optimizing treatments for metastatic melanoma (MM) by developing cell membrane (CM)-modified nanoparticles (NPs) using microfluidics, which enhance drug delivery and targeting.
- The researchers performed a direct membrane fusion process using synthetic liposomes and CM from MM cell lines, loading these hybrid liposomes with targeted agents like cobimetinib and lenvatinib.
- Results showed that these hybrid liposomes had significantly better targeting and effectiveness against MM cells compared to standard liposomes or free drugs, while demonstrating low toxicity.
Article Synopsis
- * The effectiveness of these nanoparticles relies on their specific surface design, leading to the creation of biomimetic nanoparticles as innovative drug carriers.
- * This review highlights the benefits of using microfluidic technology for the fabrication of biomimetic nanoparticles, showcasing its advantages in production efficiency, scalability, and potential to advance personalized medicine.
