Publications by authors named "Dafeng Xie"
Article Synopsis
- The fibroblast-myofibroblast transition is crucial in wound healing, involving ECM secretion and the contraction of stress fibers.
- The study introduces a cell membrane-based nanoplatform using myofibroblast membranes and gold nanoparticles loaded with IL-4 to enhance wound healing and improve bacterial clearance.
- This novel approach promotes the transition of primitive fibroblasts to myofibroblasts, facilitating matrix production, vascularization, and epithelial regeneration for better wound closure.
The (M2M + TGF-β)@HAMA hydrogel dressing improves the outcomes of dysregulated chronic wound healing by protecting the open wound from repeated bacterial infections, reprogramming endogenous monocytes and M1 macrophages into an M2-phenotype, as well as enhancing fibroblastic proliferation and migration for matrix remodeling and granulation tissue formation.Image 1.
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