Publications by authors named "DaeHee Kim"

Background And Objectives: Among various emerging catheter-based treatments for severe tricuspid regurgitation (TR), the spacer device can reduce the regurgitation orifice without manipulating the valve leaflet. However, its clinical application has been hampered by traumatic anchoring to the myocardium and the coaxial alignment of the balloon resulting in insufficient TR reduction. This study aimed to evaluate the early-stage safety, technical feasibility, and preliminary efficacy of the novel atraumatic vertical spacer in patients with isolated severe TR.

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  • This study investigates the link between lipoprotein(a) levels and the risk of developing severe degenerative aortic stenosis (AS), which can lead to aortic valve replacement (AVR).
  • Among 44,742 patients followed for an average of 6.8 years, those with Lp(a) levels greater than 100 mg/dL had a significantly higher risk for severe AS and needing AVR compared to those with lower levels.
  • The findings suggest that high Lp(a) levels specifically increase the risk for severe degenerative AS, but this association does not apply to other forms of AS, like severe bicuspid or rheumatic AS.
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The present study was designed to identify the preoperative clinical and imaging findings influencing adverse clinical outcomes in patients with chronic constrictive pericarditis after pericardiectomy. Patients with constrictive pericarditis who underwent pericardiectomy between January 2009 and September 2023 were retrospectively analyzed. Preoperative evaluations included assessments of clinical symptoms, comorbidities, laboratory tests, cardiac computed tomography (CT), and transthoracic echocardiography.

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This study aimed to investigate the characteristics of out-of-office blood pressure (BP) measurements in patients with apparent treatment-resistant hypertension (aRH) enrolled from 15 tertiary care centers in South Korea. aRH was defined as having uncontrolled office BP ≥ 130/80 mmHg despite receiving three classes of antihypertensive medication or any level of BP despite receiving ≥4 classes of antihypertensive medication. Patients with complete data for office BP, 24-h ambulatory BP monitoring (ABPM), and home BP measurements at baseline were included.

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  • - The study focuses on idiopathic pulmonary arterial hypertension (IPAH), a severe condition with a poor prognosis, aiming to explore the significance of chest CT and heart contour changes in predicting adverse outcomes for patients.
  • - An analysis of 80 IPAH patients revealed a 3-year survival rate of 65.8%, with several factors such as cardiac arrest history and specific imaging findings correlated with higher risks for adverse events like death or lung transplantation.
  • - The combined use of clinical data, chest CT, and chest X-ray findings increased event-free survival prediction accuracy to 82.2%, suggesting that monitoring these imaging parameters could help identify patients needing more aggressive treatment.
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  • The study evaluated the effectiveness of using 3D transesophageal echocardiography to determine balloon size for percutaneous mitral balloon commissurotomy (PMBC) in patients with mitral stenosis (MS).
  • Traditional methods of selecting balloon size rely on a patient's height or body surface area, which may not be as accurate as the new approach based on mitral valve measurements.
  • Results showed that using optimized formulas for balloon size selection led to different outcomes in groups with successful PMBC, residual MS, or significant mitral regurgitation (MR), suggesting that 3D measurements can improve treatment efficacy.
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  • Stacking semiconductor chips enhances packing density and efficiency, leading to better performance, speed, and lower power usage.
  • Traditional Cu to Cu direct bonding (CCDB) requires high temperatures above 250 °C to prevent oxidation, which limits its practical applications.
  • A new method using a 6 nm Ru layer allows for reliable bonding at temperatures as low as 200 °C, achieving strong connections and stability in extreme temperature cycles.
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Purpose: Therapeutic hypothermia (TH) is widely acknowledged as one of the interventions for preventing hypoxic ischemic brain injury in comatose patients following cardiac arrest (CA). Despite its recognized efficacy, recent debates have questioned its effectiveness. This preclinical study evaluated the impact of TH on brain glucose metabolism, utilizing fluorine-18-fluorodeoxyglucose (F-FDG) positron emission tomography (PET) in a rat model of CA.

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  • The study investigated the effectiveness of balloon pulmonary angioplasty (BPA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) using specialized lung imaging techniques (SPECT/CT) to measure lung blood flow.
  • Researchers analyzed data from 24 patients before and after BPA, scoring lung perfusion defects and examining their correlation with various health parameters.
  • Results showed a significant improvement in lung perfusion scores and other metrics after BPA, suggesting that this imaging approach could serve as a useful tool for assessing the treatment's success.
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Background: Police officers face an increased risk of developing cerebro-cardiovascular diseases (CVD). However, current literature lacks population-based cohort studies specifically focusing on this association. This study aimed to investigate the association between police officers and the risk of developing CVD compared with education officers, while accounting for socioeconomic and demographic factors.

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With the introduction of deep learning, a significant amount of research has been conducted in the field of computer vision in the past decade. In particular, research on object detection (OD) continues to progress rapidly. However, despite these advances, some limitations need to be overcome to enable real-world applications of deep learning-based OD models.

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Acetaminophen overdose is a leading cause of acute liver failure (ALF), and effective treatment depends on early prediction of disease progression. ALF diagnosis currently requires blood collection 24-72 h after APAP ingestion, necessitating repeated tests and hospitalization. Here, we assessed earlier ALF diagnosis using positron emission tomography (PET) imaging of translocator proteins (TSPOs), which are involved in molecular transport, oxidative stress, apoptosis, and energy metabolism, with the radiotracer [F]GE180.

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Understanding brain function is essential for advancing our comprehension of human cognition, behavior, and neurological disorders. Magnetic resonance imaging (MRI) stands out as a powerful tool for exploring brain function, providing detailed insights into its structure and physiology. Combining MRI technology with electrophysiological recording system can enhance the comprehension of brain functionality through synergistic effects.

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This study evaluated an oscillometric device (OD), Microlife WatchBP Office AFIB, and a hybrid manual auscultatory device (AD), Greenlight 300TM, to determine a suitable blood pressure (BP) measurement device for the Korea National Health and Nutrition Examination Survey in a mercury-free context. Adhering to the 2018 Universal Standard's suggested consensus, the study involved 800 subjects (mean age 51.2 ± 17.

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  • This study aimed to evaluate how well perfusion-only SPECT/CT (Q SPECT/CT) diagnoses chronic thromboembolic pulmonary hypertension (CTEPH) compared to other imaging methods like V/Q planar and V/Q SPECT/CT.
  • Researchers analyzed data from 192 patients, assessing the sensitivity and specificity of each imaging technique using a comprehensive reference standard that included pulmonary angiography.
  • Q SPECT/CT showed high sensitivity (98.8%), similar to other methods, but had significantly lower specificity (73.8%), particularly in patients aged 50 and older, indicating that ventilation scans may still be crucial in diagnosing pulmonary hypertension.
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  • The study focuses on left atrial thrombus (LAT) formation in patients with atrial fibrillation (AF) already on anticoagulation therapy for over 4 weeks, highlighting its link to thromboembolic events.
  • The research analyzed 1,122 patients and found that LAT was present in 5.3% of them, with factors like age, type of AF, CHADS-VASc score, left ventricular ejection fraction, and atrial enlargement influencing its presence.
  • A predictive model combining these clinical and echocardiographic factors showed strong performance, indicating it could help identify patients who might need further imaging before treatment interventions.
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  • * An analysis of 1215 patients found that both DOACs and warfarin had similar risks for ischemic stroke and major bleeding; however, DOACs were associated with a lower risk of intracranial hemorrhage.
  • * The findings suggest that DOACs are effective and safe alternatives to warfarin for treating atrial fibrillation in patients with significant TR, maintaining similar efficacy for major complications.
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In participants who underwent valve-in-valve transcatheter aortic valve replacement, hypoattenuating intra-annular material within the failed surgical bioprostheses reduced the CT-derived internal area and interfered with expansion of intra-annular-positioned implanted valves, leading to postprocedural patient-prosthesis mismatch.

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Purpose: To evaluate the relationship between prospectively generated ablative margin estimates and local tumor progression (LTP) among patients undergoing microwave ablation (MWA) of small renal masses (SRMs).

Materials And Methods: Between 2017 and 2020, patients who underwent MWA for SRM were retrospectively identified. During each procedure, segmented kidney and tumor shapes were coregistered with intraprocedural helical CT images obtained after microwave antenna placement.

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  • - Subclinical thrombus formation at the aortic valve complex (including valvular and perivalvular) occurs frequently after transcatheter aortic valve replacement (TAVR), affecting about 43% of patients in the study.
  • - The study identified small stent diameter and low body surface area as independent predictors of thrombus formation, with decreased renal function linked to leaflet thrombus specifically.
  • - Despite the high incidence of thrombus after TAVR, there were no significant changes in neurological outcomes or new cerebral lesions among patients, indicating that the presence of thrombus may not impact clinical outcomes significantly.
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  • The study investigates the risk of leaflet thrombosis and cerebral thromboembolism in patients undergoing transcatheter aortic valve replacement (TAVR), comparing the effects of low-dose and standard-dose edoxaban versus dual antiplatelet therapy (DAPT).
  • Results showed that standard-dose edoxaban significantly reduced the incidence of leaflet thrombosis (2.4%) compared to DAPT (18.3%), while low-dose edoxaban had no significant advantage over DAPT (15.0% vs 18.3%).
  • Despite the differences in leaflet thrombosis rates, there were no significant changes in new cerebral lesions or neurological dysfunction among the groups.
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Mitral valve disease is the most common valvular heart disease. Imaging determines the etiology (anatomic assessment), valve function and severity of valvular heart disease (hemodynamic assessment), remodeling of the left ventricle and right ventricle, and preplanning and guidance of percutaneous intervention. Although roles of computed tomography and magnetic resonance are increasing, echocardiography serves as the first-line imaging modality for the diagnosis and serial follow-up in most cases.

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Objective: To compare the clinical outcomes of aortic valve replacement (AVR) using bovine pericardial and porcine bioprostheses, utilizing a nationwide administrative claims database.

Methods: Adult patients (age ≥40 years) who underwent bioprosthetic AVR, without other valve replacements, between 2003 and 2018 were identified from the Korean National Health Insurance Service database. The outcomes of interest were all-cause mortality, cardiac mortality, and valve-related events, including the incidence of reoperation, endocarditis, systemic thromboembolism, and major bleeding.

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