Association between depression and young-onset dementia in middle-aged women.

Background: Dementia is associated with older adults; however, it can also affect younger individuals, known as young-onset dementia (YOD), when diagnosed before the age of 65 years. We aimed to conduct a retrospective cohort study involving middle-aged women to investigate the association between premorbid depression and YOD development.

Methods: We included 1.

Self-Powered Water Splitting of NiFeN@FeN Bifunctional Catalyst Improved Catalytic Activity and Durability by Forming FeN on Catalyst Surface via the Kirkendall Effect.

Highly efficient water splitting electrocatalyst for producing hydrogen as a renewable energy source offers potential to achieve net-zero. However, it has significant challenges in using transition metal electrocatalysts as alternatives to noble metals due to their low efficiency and durability, furthermore, the reliance on electricity generation for electrocatalysts from fossil fuels leads to unavoidable carbon emissions. Here, a highly efficient self-powered water splitting system integrated is designed with triboelectric nanogenerator (TENG) and NiFeN@FeN catalyst with improved catalytic activity and durability.

Wafer-Scale Atomic Assembly for 2D Multinary Transition Metal Dichalcogenides for Visible and NIR Photodetection.

The tunable properties of 2D transition-metal dichalcogenide (TMDs) materials are extensively investigated for high-performance and wavelength-tunable optoelectronic applications. However, the precise modification of large-scale systems for practical optoelectronic applications remains a challenge. In this study, a wafer-scale atomic assembly process to produce 2D multinary (binary, ternary, and quaternary) TMDs for broadband photodetection is demonstrated.

Promoted Overall Water Splitting Catalytic Activity and Durability of NiFe Alloy by Designing N-Doped Carbon Encapsulation.

Combining an electrochemically stable material onto the surface of a catalyst can improve the durability of a transition metal catalyst, and enable the catalyst to operate stably at high current density. Herein, the contribution of the N-doped carbon shell (NCS) to the electrochemical properties is evaluated by comparing the characteristics of the NiFe@NCS catalyst with the N-doped carbon shell, and the NiFe catalyst. The synthesized NiFe@NCS catalyst has a distinct overpotential difference from the NiFe catalyst (η = 468.

Deep Learning of Speech Data for Early Detection of Alzheimer's Disease in the Elderly.

Background: Alzheimer's disease (AD) is the most common form of dementia, which makes the lives of patients and their families difficult for various reasons. Therefore, early detection of AD is crucial to alleviating the symptoms through medication and treatment.

Objective: Given that AD strongly induces language disorders, this study aims to detect AD rapidly by analyzing the language characteristics.

Improving performance robustness of subject-based brain segmentation software.

Purpose: Artificial intelligence (AI)-based image analysis tools to quantify the brain have become commercialized. However, insufficient data for learning and scanner specificity is a limitation for achieving high quality. In the present study, the performance of personalized brain segmentation software when applied to multicenter data using an AI model trained on data from a single institution was improved.

Risk Factors for Various Cognitive Function Decline Trajectories in Adults Over 40 Years of Age: A Retrospective Cohort Study.

Objective: The aims of our study were to identify distinct trajectories of cognitive function using the group-based trajectory model. We also investigate which demographic factors act as risk factors for cognitive decline in each group.

Methods: The data from the Seoul National University Hospital Healthcare System Gangnam Center, from 2005 to 2019.

Citrous Lime-A Functional Reductive Booster for Oil-Mediated Green Synthesis of Bioactive Silver Nanospheres for Healthcare Clothing Applications and Their Eco-Mapping with SDGs.

Silver nanoparticles (Ag-NPs) are most effective against pathogens and have widely been studied as antibacterial agents in commodity clothing, medical textile, and other hygiene products. However, prolonged utilization of silver and rapid mutation in bacterium stains has made them resistant to conventional silver agents. On the other hand, strict compliance against excessive utilization of toxic reagents and the current sustainability drive is forcing material synthesis toward green routes with extended functionality.

Fabrication of phosphor in glass using waste glass for automotive lighting application.

With advancement of technology, requirements for light-emitting devices are increasing. Various types of packaging technologies have been suggested to improve the performance of light-emitting diode (LED). Among them, phosphor in glass (PiG) is attracting attention due to its manufactural facility and easily tunable characteristics.

Preparation of high-quality YAG:Ce ceramic phosphor by high-frequency induction heated press sintering methods.

This study investigates the characteristics of a ceramic phosphor (CP) for the converter of a high-power laser diode-based automobile headlamp synthesized by high-frequency induction heated press (HFP) sintering. The CP prepared by an HFP method exhibits remarkable optical properties that are comparable to spark plasma sintering. The effects of post-treatment process for controlling residual pores, as well as sintering temperature, sintering pressure and heating rate for optimization of the HFP sintering method, were studied.

Supercritical Extract of Inhibits Lung Metastasis in Colorectal Cancer Cells by Increasing AMPK and MAPKs-Mediated Apoptosis and Cell Cycle Arrest.

Colorectal cancer (CRC) is one of the diseases with the highest rates of prevalence and mortality despite therapeutic methods in the world. In particular, there are not enough methods to treat metastasis of CRC cells to distant organs. Linne () is a popular medicinal plant used by humans to treat many diseases.

Tannic acid modified antifreezing gelatin organohydrogel for low modulus, high toughness, and sensitive flexible strain sensor.

Current hydrogel strain sensors have met assorted essential requirements of wearing comfort, mechanical toughness, and strain sensitivity. However, an increment in the toughness of a hydrogel usually leads to an increase in elastic moduli that could be unfavorable for wearing comfort. In addition, traits of biofriendly and sustainability require synthesis of the hydrogels from natural polymer-based networks.

Dehydroevodiamine inhibits lung metastasis by suppressing survival and metastatic abilities of colorectal cancer cells.

Background: Despite the rising 5-year survival rate of colorectal cancer (CRC) patients, the survival rate decreases as the stage progress, and a low survival rate is highly associated with metastasis.

Purpose: The purpose of our study is to investigate the effect of dehydroevodiamine (DHE) on the lung metastasis of CRC and the proliferation of CRC cells.

Study Design: Cell death was confirmed after DHE treatment on several CRC cell lines.

Copper nanoparticles induced, trimesic acid grafted cellulose-an effective, non-hazardous processing approach for multifunctional textile with low chemical induction.

Abstract: Cross-linkers have great importance in textile due to the widespread utilization of cellulosic fibers for clothing. Unfortunately, the acute toxicity of formaldehyde-based resins and the poor performance of non-formaldehyde resins still keep the research door open for scientists in this area. Herein, we demonstrated copper nanoparticles induced trimesic acid grafted cellulose as a sustainable solution for multifunctional easy-care clothing.

Strategic Customization of Polymeric Nanocomposites Modified by 2D Titanium Oxide Nanosheet for High-k and Flexible Gate Dielectrics.

Organic polymer-based dielectrics with intrinsic mechanical flexibility and good processability are excellent candidates for the dielectric layer of flexible electronics. These polymer films can become even more rigid and electrically robust when modified through cross-linking processes. Moreover, the composites formed by dispersing nanoscale inorganic fillers in a polymer matrix can exhibit further improved polarization property.

The Extract of L. Fruit (Arctii Fructus) Improves Cancer-Induced Cachexia by Inhibiting Weight Loss of Skeletal Muscle and Adipose Tissue.

Background: Cachexia induced by cancer is a systemic wasting syndrome and it accompanies continuous body weight loss with the exhaustion of skeletal muscle and adipose tissue. Cancer cachexia is not only a problem in itself, but it also reduces the effectiveness of treatments and deteriorates quality of life. However, effective treatments have not been found yet.

Fabrication of Highly Stable Fully-Inorganic Halide Perovskite Films for Optoelectronic Application.

Despite the fact that stability is a critical issue affecting halide perovskite after the materials have been developed, these materials continue to be studied due to their outstanding optoelectronic characteristics such as narrow emission band width, high PLQY. Many methods are suggested and improved, but the limitations for the display and lighting applications are still remaining. Here, we propose the fabrication of stable cesium lead tri-halide (CsPbX₃; X= Cl, Br, I) perovskite films using photocurable polyurethane material, norland optical adhesive 63 (NOA 63), to generate white LEDs by placing films on the InGaN 450 nm blue chip.

Sensory Adaptation and Neuromorphic Phototransistors Based on CsPb(BrI) Perovskite and MoS Hybrid Structure.

Sensory adaptation is an essential part of biological neural systems for sustaining human life. Using the light-induced halide phase segregation of CsPb(BrI) perovskite, we introduce neuromorphic phototransistors that emulate human sensory adaptation. The phototransistor based on a hybrid structure of perovskite and transition-metal dichalcogenide (TMD) emulates the sensory adaptation in response to a continuous light stimulus, similar to the neural system.

Flexible Graphite/PPG Hybrid Composite-Based Resistive Sensor for Sensing Organic Compounds.

Our objective in this study was to investigate a sensor for volatile organic compounds based on a graphite (G)/polypropylene glycol (PPG) hybrid composite (HC) for sensing hybrid elements. The G/PPG HC sensor films for organic-matter detection were successfully fabricated on polyethylene terephthalate (PET) film with a simple blade-coating method. The sensing paste based on G/PPG (1:2) HC showed good dispersibility and stability.

Effect of Nakai Ethanol Extract and Decursin on Human Pancreatic Cancer Cells.

Pancreatic cancer (PC) is one of the most severe cancers, and its incidence and mortality rates have steadily increased in the past decade. In this study, we demonstrate the effect of Nakai extract on pancreatic ductal adenocarcinoma cells. We prepared Nakai ethanol extract (AGE) using roots of Nakai and detected its active compound decursin from AGE by ultra-performance liquid chromatography analysis.