Transport distraction osteogenesis with recombinant human bone morphogenic protein-2 for large calvarial defect reconstruction.

Background: Transport distraction osteogenesis (TDO) has been used in attempts to treat large calvarial defects but has, until now, lacked consistency and reliability. To achieve sufficient bone formation, the effect of TDO was compared to the effect of TDO combined with recombinant human bone morphogenic protein-2 (rhBMP-2).

Methods: Fourteen dogs were divided into 2 groups; 6 animals in the control group received TDO only, and 8 received TDO combined with rhBMP-2.

Transport disc distraction osteogenesis for the reconstruction of a calvarial defect.

Purpose: According to previous reports about the experimental study of transport disk distraction osteogenesis (TDDO) for the reconstruction of bone defects, TDDO showed great feasibility of successful bone regeneration. However, those studies had some limitations in their design and analysis of the results, either. In this report, we intended to verify the effect of TDDO in the reconstruction of skull defects with a combined result of distraction osteogenesis and bone graft of transported disk (TD).

Effect of input waveform pattern and large blood vessel existence on destruction of liver tumor using radiofrequency ablation: finite element analysis.

Much research has been directed at improving the effectiveness of the radiofrequency (RF) ablation of hepatocellular carcinomas. In that point of view, this study was performed to provide comprehensive information of the relation between RF waveforms and thermodynamic response of the tissue with the consideration of four different types of RF waveforms (half-sine, half-square, half-exponential, and damped-sine) to maximize the amount of tumor tissue removed while maintaining the advantages of RF ablation. For the aim of this study, finite element models incorporating results from previous numerical models were used and validated with ex vivo experiments.

Low-intensity ultrasound stimulation prevents osteoporotic bone loss in young adult ovariectomized mice.

Osteoporosis is a disease characterized by low bone mass, increased bone fragility, and a greater risk for bone fracture. Currently, pharmacological intervention can generally aid in the prevention and treatment of osteoporosis, but these therapies are often accompanied by undesirable side effects. Therefore, alternative therapies that minimize side effects are necessary.

Mechanical properties of blood-mixed polymethylmetacrylate in percutaneous vertebroplasty.

Study Design: Mechanical study of polymethylmetacrylate (PMMA) mixed with blood as a filler.

Purpose: An attempt was made to modify the properties of PMMA to make it more suitable for percutaneous vertebroplasty (PVP).

Overview Of Literature: The expected mechanical changes by adding a filler into PMMA included decreasing the Young's modulus, polymerization temperature and setting time.

Evaluation of the potential clinical application of low-intensity ultrasound stimulation for preventing osteoporotic bone fracture.

This study evaluated the possible clinical application of low-intensity ultrasound (LIUS) stimulation for preventing osteoporotic bone fracture. Eight virgin 14-week-old ICR mice (weight 24.0 +/- 0.

Transport disc distraction osteogenesis for the reconstruction of a calvarial defect.

Purpose: Reconstruction of bone defects is possible through distraction osteogenesis using small bone transport discs. The aim of this study was to evaluate the usability of transport disc distraction osteogenesis (TDDO) in the reconstruction of skull defects in an animal experiment.

Methods: Eleven mongrel female dogs were used.