Publications by authors named "Dae Chul Cho"

The development of minimally invasive spinal surgery utilizing navigation and robotics has significantly improved the feasibility, accuracy, and efficiency of this surgery. In particular, these methods provide improved accuracy of pedicle screw placement, reduced radiation exposure, and shortened learning curves for surgeons. However, research on the clinical outcomes and cost-effectiveness of navigation and robot-assisted spinal surgery is still in its infancy.

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Objective: Although several studies have reported successful fusion rates after oblique lumbar interbody fusion (OLIF) using allografts or dimerized bone matrix (DBM) instead of autografts, whether OLIF can achieve satisfactory solid fusion without the use of autografts remains unclear. This study investigated the real fusion rates after OLIF using allografts and DBM, which were evaluated using both dynamic radiographs and computed tomography scans.

Methods: We enrolled 79 consecutive patients who underwent minimally invasive OLIF followed by percutaneous pedicle screw fixation.

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Background Context: Electrical stimulation is a noninvasive treatment method that has gained popularity in the treatment of spinal cord injury (SCI). Activation of spinal cord-derived neural stem/progenitor cell (SC-NSPC) proliferation and differentiation in the injured spinal cord may elicit considerable neural regenerative effects.

Purpose: This study aimed to explore the effect of electrical stimulation on the neurogenesis of SC-NSPCs.

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Tuberculous spondylitis often develops catastrophic bone destruction with uncontrolled inflammation. Because anti-tuberculous drugs do not have a role in bone formation, a combination drug therapy with a bone anabolic agent could help in fracture prevention and promote bone reconstruction. This study aimed to investigate the influence of teriparatide on the effect of anti-tuberculous drugs in tuberculous spondylitis treatment.

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Article Synopsis
  • The study aimed to identify criteria for successful atlantoaxial (AA) fusion by analyzing the outcomes of patients who underwent the procedure, using follow-up imaging.
  • Out of 161 patients analyzed, 49 were included based on having at least a year of follow-up; 91.8% achieved successful bone fusion, while 28.6% exhibited screw halos, which did not significantly affect fusion failure rates.
  • A notable finding was that a larger segmental angle (SA) gap during flexion-extension dynamic radiographs correlated with an increased risk of fusion failure, specifically when the SA gap exceeded 2.62°.
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Objective: Neuropathic pain is a common secondary complication of spinal cord injury (SCI). N-methyl-D-aspartate (NMDA) receptor activation is critical for hypersensitivity in neuropathic pain. This activation requires the binding of both glutamate and the D-serine co-agonist to the NMDA glycine site.

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Article Synopsis
  • The study aimed to compare the outcomes of two types of spinal fusion surgeries: Transforaminal Lumbar Interbody Fusion (TLIF) and Oblique Lumbar Interbody Fusion (OLIF) in patients undergoing revision surgery.
  • It involved 50 patients (25 OLIF, 25 TLIF) and assessed various metrics, including spinal canal cross-sectional area and patient-reported pain and disability levels post-surgery.
  • The findings suggested that while both methods improved patient outcomes, OLIF had fewer complications and may be a safer minimally invasive alternative to TLIF for revision surgeries.
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Background Context: Although the surgical corridor used for oblique lateral interbody fusion (OLIF) protects the intrapsoas nerves by causing minimal compression, transient weakness remains the most commonly reported postoperative complication.

Purpose: Using a dynamometer to evaluate how the hip flexor strength changes following OLIF.

Study Design/setting: A prospective observational study.

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Curcumin is a polyphenolic chemical derived from the rhizomes of Curcuma longa. It has been used throughout the Indian subcontinent for medicinal purposes, religious events, and regional cuisine. It has various pharmacological benefits owing to its anti-inflammatory and antioxidant properties.

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Objective: Oblique lumbar interbody fusion (OLIF) involves inserting large cages into the interbody disc space. This expands the spinal canal and neural foramen by stretching the ligament flavum and releasing the facet joint, resulting in indirect neural decompression. Our objective was to investigate the changes in the spinal canal and ligament flavum over time after OLIF.

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Spinal epidural arteriovenous fistula (SEDAVF) is a rare vascular malformation. Due to the mass effect of enlarged epidural veins and venous hypertension, progressive radiculopathy and myelopathy are likely to occur. A 33-year-old female presented with right upper extremity weakness for a month.

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Introduction: Tuberculosis (TB) spondylitis, also known as Pott's disease, is a severe form of extrapulmonary TB. Infliximab treatment for Crohn's disease (CD) patients increases the risk of TB, and is likely to increase the risk of TB spondylitis as well.

Case Presentation: We report a rare case of TB spondylitis development in a 16-year-old female with CD.

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We have analyzed and compared the publication trends in 4 representative spinal journals [Spine, European Spinal Journal (EUS), The Spine Journal (TSJ), and the Journal of Neurosurgery - Spine (JNS spine)] from 2016 to 2018.A total of 3784 articles were published in the 4 representative journals: 1358, 1128, 685, and 613 articles in Spine, EUS, TSJ, and JNS spine, respectively. We compared and analyzed each periodical for the time taken (days) for the publication process, the distribution of specialties of the corresponding author, multicity of the investigative institutions, main disease entity, study type, and design.

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Objective: Cerebrospinal fluid leakage related complications (CLC) occasionally occur after intradural spinal surgery. We sought to investigate the effectiveness of early ambulation after intradural spinal surgery and analyze the risk factors for CLC.

Methods: For this retrospective cohort study, we enrolled 314 patients who underwent intradural spinal surgery at a single institution.

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Objective: The period of mechanical ventilator (MV)-dependent respiratory failure after cervical spinal cord injury (CSCI) varies from patient to patient. This study aimed to identify predictors of MV at hospital discharge (MVDC) due to prolonged respiratory failure among patients with MV after CSCI.

Methods: Two hundred forty-three patients with CSCI were admitted to our institution between May 2006 and April 2018.

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Objective: Cauda equina tumors affect the peripheral nervous system, and the validities of triggered electromyogram (tEMG) and intraoperative neurophysiologic monitoring (IOM) are unclear. We sought to evaluate the accuracy and relevance of tEMG combined with IOM during cauda equina tumor resection.

Methods: Between 2008 and 2018, an experienced surgeon performed cauda equina tumor resections using tEMG at a single institution.

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Objective: To compare the anterior cervical discectomy and fusion (ACDF) and posterior cervical fusion (PCF) with wide facetectomy in the treatment of parallel-shaped bony foraminal stenosis (FS).

Methods: Thirty-six patients underwent surgery due to one-or-two levels of parallel-shaped cervical FS. ACDF was performed in 16 patients, and PCF using CPS was performed in 20 patients.

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Objective: Oblique lumbar interbody fusion (OLIF) is useful as surgical treatment of degenerative lumbar disease. However, revision surgery has often resulted in worse surgical outcomes than primary surgery. Thus, we compared the usefulness of OLIF as primary surgery (PS) versus revision surgery (RS).

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Study Design: Retrospective comparative study.

Objective: The aim of this study was to compare cervical sagittal alignment after posterior fusion surgery with lateral mass screw (LMS) and cervical pedicle screw (CPS) fixation.

Summary Of Background Data: LMS fixation in the subaxial cervical spine has become the preferred method of posterior cervical fusion.

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Objective: To analyze the electrical resistance of a newly developed neuromonitoring pedicle screw (Neuro-PS) and to verify the electrophysiologic properties of the Neuro-PS in a pig model.

Methods: We developed 2 types of the Neuro-PS in which a gold lead was located internally (type I) and externally (type II). We measured the electrical resistance of the Neuro-PS and the conventional screw and analyzed the electrical thresholds of triggered EMG (t-EMG) of each screw by intentionally penetrating the medial pedicle wall and contacting the exiting nerve root in a pig model.

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Article Synopsis
  • The COVID-19 pandemic has led to a higher demand for testing methods, with RT-PCR being the most definitive but slower option for diagnosis.
  • This study explores using a deep learning-based decision-tree classifier to analyze chest X-ray images for COVID-19 detection and related pneumonia.
  • The classifier features three decision trees, achieving high accuracy rates (98% for normal vs. abnormal images, 80% for tuberculosis detection, and 95% for COVID-19), potentially speeding up patient triage before RT-PCR results come in.
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Article Synopsis
  • Researchers compared two surgical approaches, a conventional open approach (OA) and a contralateral muscle preserving approach (MPA), for laminoplasty in patients with cervical myelopathy to see which better preserved posterior cervical muscles.
  • The study involved 44 patients and measured the changes in muscle size before and after surgery using CT scans.
  • Results showed that MPA had significantly better preservation of the multifidus and semispinalis cervicis muscles compared to OA, making it a more effective option for reducing postoperative complications, especially at the C3-4 level.
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