Conventional SiC alpha particle radiation detectors typically operate under an applied bias of tens to hundreds of volts. This study introduces a self-powered alpha particle detector using an AlScN/SiC heterojunction structure. By optimizing the thickness of the AlScN film, the detector achieves a low dark current (1.
View Article and Find Full Text PDFHere, we have designed a novel, to the best of our knowledge, three-terminal AlGaN-based deep-ultraviolet (DUV) laser diode (LD), featuring an AlScN ferroelectric layer beneath the third terminal and a stepped ridge structure. Our findings indicate that when the AlScN layer is negatively polarized by an external bias by the third terminal, the fixed polarization positive charges at the AlScN/p-GaN interface can enhance hole injection efficiency by modulating the energy band in the p-type region near the AlScN layer. The modulation does not deteriorate the electron injection and the optical field confinement, thus effectively increasing the stimulated recombination rate in the active region.
View Article and Find Full Text PDFA UPLC-MS/MS method with one-step extraction and simultaneous determination of bongkrekic acid (BA) and dehydroacetic acid (DHA) in rice noodles has been established in this study for the first time. The extraction solvent consisted of a mixture of methanol, ammonia, and water. Electrospray ionization negative ion mode (ESI-) was used for multiple reaction detection and external standard method was used for quantitative determination.
View Article and Find Full Text PDFPolarization is an important attribute of light and can be artificially modulated as a versatile information carrier. Conventional polarization-sensitive photodetection relies on a combination of polarizing optical elements and standard photodetectors, which requires a substantial amount of space and manufacturing expenses. Although on-chip polarized photodetectors have been realized in recent years based on two-dimensional (2D) materials with low-symmetry crystal structures, they are limited by the intrinsic anisotropic property and thus the optional range of materials, the operation wavelength, and more importantly, the low anisotropic ratio, hindering their practical applications.
View Article and Find Full Text PDFMoisture-electric generators (MEGs) generate power by adsorbing water from the air. However, their performance at low temperatures is hindered due to icing. In the present work, MEG arrays are developed by laser engraving techniques and a modulated low-temperature hydrogel as the absorbent material.
View Article and Find Full Text PDFThe integrated approach of interfacial engineering and composite electrolytes is crucial for the market application of Li metal batteries (LMBs). A 22 μm thin-film type polymer/LiLaZrTaO (LLZTO) composite solid-state electrolyte (LPCE) was designed that combines fast ion conduction and stable interfacial evolution, enhancing lithium metal interface stability and cycling performance. The ether-based molecular coordination groups/clusters formed by triethylene glycol dimethyl ether (TGDE) and anions facilitated the movement of Li between the polymer chain segments.
View Article and Find Full Text PDFApplying the orthogonal principle for distinguishable second near-infrared (NIR-II) emissions has brought new dimensions for ratio fluorescence imaging (RFI) detection and information encryption, deepening the tissue detection depth and improving signal-to-noise ratio and information security. However, the orthogonal NIR-II emissions underlying these advanced optical applications have been reported only in heterogeneous structures and mixtures, limiting their practicality and potential impact. Herein, NIR-I-activated orthogonal NIR-IIb/c (1530/1825 nm) emissions nanoparticles (ONNPs) are developed by spatially separated doping of Tm and Er emitter upon switching 808 and 980 nm excitations.
View Article and Find Full Text PDFAsymmetric doping of wide-gap semiconductors has long been a major challenge, hindering their wider applications. Despite numerous attempts to address this issue through engineering doping levels, the results were still inconclusive. In this work, we propose a quantum engineering strategy based on the state-of-the-art spin-polarized HSE06 hybrid functional method.
View Article and Find Full Text PDFENG/CD105 encodes a vascular endothelial glycoprotein and plays a crucial role in modulating angiogenesis. However, the significance of ENG expression, DNA methylation, immuno-response, and cordycepin (CD) regulation as diagnostic, prognostic, and therapeutic markers for breast invasive carcinoma (BRCA) remains unclear. As a result, ENG is decreased in BRCA tissues compared with corresponding healthy tissues.
View Article and Find Full Text PDFThe Gasdermin E gene (GSDME) plays roles in deafness and cancers. However, the roles and mechanisms in cancers are complex, and the same gene exhibits different mechanisms and actions in different types of cancers. Online databases, such as GEPIA2, cBioPortal, and DNMIVD, were used to comprehensively analyze GSDME profiles, DNA methylations, mutations, diagnosis, and prognosis in patients with tumor tissues and matched healthy tissues.
View Article and Find Full Text PDFSchizophrenia (SZ) is a chronic, severe mental disorder with heterogeneous clinical manifestations and unknown etiology. Research on SZ has long been limited by the low reliability of and ambiguous pathogenesis in schizophrenia animal models. Phencyclidine (PCP), a noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist, rapidly induces both positive and negative symptoms of SZ as well as stable SZ-related cognitive impairment in rodents.
View Article and Find Full Text PDFThe paper presents a wide-bandwidth, low-polarization semiconductor optical amplifier (SOA) based on strained quantum wells. By enhancing the material gain of quantum wells for TM modes, we have extended the gain bandwidth of the SOA while reducing its polarization sensitivity. Through a combination of tilted waveguide design and cavity surface optical thin film design, we have effectively reduced the cavity surface reflectance of the SOA, thus decreasing device transmission losses and noise figure.
View Article and Find Full Text PDFAlGaN-based solar-blind ultraviolet avalanche detectors have huge potentials in the fields of corona discharge monitoring, biological imaging, etc. Here, we study the impact of the heterojunction polarization-related effects on the AlGaN-based solar-blind ultraviolet avalanche detectors. Our work confirms that the polarization heterojunction is beneficial to reducing avalanche bias and lifting avalanche gain by improving the electric field in the depletion region, while the polarization-induced fixed charges will lead to a redistribution of the electrons, in turn shielding the charges and weakening the electric field enhancement effect.
View Article and Find Full Text PDFSARS-CoV-2 has triggered an international outbreak of the highly contagious acute respiratory disease known as COVID-19. Identifying key targets in the virus infection lifecycle is crucial for developing effective prevention and therapeutic strategies against it. Furin is a serine endoprotease that belongs to the family of proprotein convertases and plays a critical role in the entry of host cells by SARS-CoV-2.
View Article and Find Full Text PDFColorectal cancer (CRC) is a major worldwide health issue, with high rates of both occurrence and mortality. Dysregulation of the transforming growth factor-beta (TGF-β) signaling pathway is recognized as a pivotal factor in CRC pathogenesis. Notably, the INHBA gene and long non-coding RNAs (lncRNAs) have emerged as key contributors to CRC progression.
View Article and Find Full Text PDFBroadband photodetectors have drawn intensive attention owing to their wide application prospects in optical communication, imaging, astronomy, and so on. Two-dimensional transition-metal dichalcogenides (TMDs) are considered as highly potential candidates for photodetection applications, benefiting from their excellent photoelectric properties. However, most of the photodetectors based on TMDs suffer from low performance in the near-infrared (NIR) region due to the weak optical absorption efficiency near their absorption band edge, which severely constrains their usage for broadband optoelectronics.
View Article and Find Full Text PDFWith the fast development of artificial intelligence (AI), Internet of things (IOT), etc, there is an urgent need for the technology that can efficiently recognize, store and process a staggering amount of information. The AlScN material has unique advantages including immense remnant polarization, superior temperature stability and good lattice-match to other III-nitrides, making it easy to integrate with the existing advanced III-nitrides material and device technologies. However, due to the large band-gap, strong coercive field, and low photo-generated carrier generation and separation efficiency, it is difficult for AlScN itself to accumulate enough photo-generated carriers at the surface/interface to induce polarization inversion, limiting its application in in-memory sensing and computing.
View Article and Find Full Text PDFIntegrating ferroelectric AlScN with III-N semiconductors to enhance the performance and tunability of nitride devices requires high-quality AlScN films. This work focuses on the effect and regulation mechanism of post-annealing in pure N on the crystal quality and ferroelectric properties of AlScN films. It is found that the crystal quality improves with increasing annealing temperatures.
View Article and Find Full Text PDFThe unique optical and electrical properties of graphene-based heterojunctions make them significant for artificial synaptic devices, promoting the advancement of biomimetic vision systems. However, mass production and integration of device arrays are necessary for visual imaging, which is still challenging due to the difficulty in direct growth of wafer-scale graphene patterns. Here, a novel strategy is proposed using photosensitive polymer as a solid carbon source for in situ growth of patterned graphene on diverse substrates.
View Article and Find Full Text PDFThe role of fat mass and obesity-associated protein (FTO), an -methyladenosine (mA) demethylase, in non-small cell lung cancer (NSCLC) has recently received widespread attention. However the underlying mechanisms of FTO-mediated autophagy regulation in NSCLC progression remain elusive. In this study, we found that was significantly upregulated in NSCLC, and downregulation of suppressed the growth, invasion and migration of NSCLC cells by inducing autophagy.
View Article and Find Full Text PDFIn solid-state lithium metal batteries (SSLMBs), the inhomogeneous electrolyte-electrode interphase layer aggravates the interfacial stability, leading to discontinuous interfacial ion/charge transport and continuous degradation of the electrolyte. Herein, we constructed an anion-modulated ionic conductor (AMIC) that enables in situ construction of electrolyte/electrode interphases for high-voltage SSLMBs by exploiting conformational transitions under multiple interactions between polymer and lithium salt anions. Anions modulate the decomposition behavior of supramolecular poly (vinylene carbonate) (PVC) at the electrode interface by changing the spatial conformation of the polymer chains, which further enhances ion transport and stabilizes the interfacial morphology.
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