Fully automatic resolution of untargeted GC-MS data with deep learning assistance.

DeepResolution (Deep learning-assisted multivariate curve Resolution) has been proposed to solve the co-eluting problem for GC-MS data. However, DeepResolution models must be retrained when encountering unknown components, which is undoubtedly time-consuming and burdensome. In this study, a new pipeline named DeepResoution2 was proposed to overcome these limitations.

A new torsion tester based on an electronic autocollimator for characterizing the torsional behaviors of microfibers.

Torsional properties of single fibers have considerable effects on the performance of fabrics. A new torsion tester with high resolution is developed based on the torsion-balance method and the autocollimation principle for measuring the torsional properties of single fibers. The tester can measure the torque accurately using the torsion wire of known torsional rigidity.

Hydroxyapatite-reinforced alginate fibers with bioinspired dually aligned architectures.

Biological materials have excellent mechanical properties due to their organized structures from nano- to macro-scale. Artificial manufacture of materials with anisotropic microstructures still remains challenging. We described a stress-induced method to fabricate anisotropic alginate fibers.

Spider dragline silk as torsional actuator driven by humidity.

Self-powered actuation driven by ambient humidity is of practical interest for applications such as hygroscopic artificial muscles. We demonstrate that spider dragline silk exhibits a humidity-induced torsional deformation of more than 300°/mm. When the relative humidity reaches a threshold of about 70%, the dragline silk starts to generate a large twist deformation independent of spider species.

Long non-coding RNA DANCR promotes the progression of non-small-cell lung cancer by inhibiting p21 expression.

Background: Long non-coding RNAs (lncRNAs) play important roles in human cancers. However, the functional roles of lncRNAs in non-small-cell lung cancer (NSCLC) and the underlying mechanisms are not well understood.

Methods: We examined the expression of lncRNA DANCR in NSCLC by qRT-PCR and explored its biological roles in NSCLC progression by cell and molecular biology studies.

Genetic polymorphisms of ERCC-1 and ERCC-2 are not prognostic markers in osteosarcoma patients with chemotherapy: A meta-analysis in Chinese population.

Aim: To make an accurate estimation of the association of ERCC1 and ERCC2 polymorphisms with osteosarcoma (OS) prognosis in Chinese population.

Methods: Total 7 qualified studies with 1404 osteosarcoma patients were included. Odds ratios (OR) with 95% CIs were pooled for the survival rate in different osteosarcoma patients with ERCC1 and ERCC2 genetic polymorphisms.

Tetrandrine suppresses β‑glucan‑induced macrophage activation via inhibiting NF‑κB, ERK and STAT3 signaling pathways.

Macrophages are important in inflammation through the production of various proinflammatory mediators. β‑glucan is a polymer of glucose, which is produced by numerous different organisms, including fungi, and acts as a trigger for the induction of inflammatory responses. Tetrandrine (TET), a bis‑benzylisoquinoline alkaloid isolated from the Chinese herb Radix Stephania tetrandra, has been demonstrated to modulate inflammatory responses.

LYN, a Key Gene From Bioinformatics Analysis, Contributes to Development and Progression of Esophageal Adenocarcinoma.

BACKGROUND Esophageal adenocarcinoma is a lethal malignancy whose incidence is rapidly growing in recent years. Previous reports suggested that Barrett's esophagus (BE), which is represented by metaplasia-dysplasia-carcinoma transition, is regarded as the premalignant lesion of esophageal neoplasm. However, our knowledge about the development of esophageal adenocarcinoma is still very limited.

Digital image frequency spectrum method for analyzing speckle displacement in frequency domain.

A technique called the digital image frequency spectrum (DIFS) method, used for analyzing digital speckle patterns with deformations in the frequency domain, is proposed. Two subimages in the same position as two digital speckle patterns before and after deformation are used to form a Young's fringe. The parallel Young's fringe pattern is automatically analyzed in the frequency domain.

Anomalous plasticity in the cyclic torsion of micron scale metallic wires.

The plasticity of micron scale Cu and Au wires under cyclic torsion is investigated for the first time by using a torsion balance technique. In addition to a size effect, a distinct Bauschinger effect and an anomalous plastic recovery, wherein reverse plasticity even occurs upon unloading, are unambiguously revealed. The Bauschinger effect and plastic recovery have been observed in molecular dynamics and discrete dislocation dynamics simulations of ideal single-crystal wires; the results here are an excellent confirmation that these effects also occur in experiment in nonideal polycrystalline wires.

[Detection of IgG and IgM antibodies against Chlamydia trachomatis in semen of asymptomatic infertile patients].

Objectives: To evaluate the clinical significance of the detection of IgG and IgM antibodies against Chlamydia trachomatis (CT) in semen of asymptomatic infertile patients.

Methods: One hundred and sixteen asymptomatic infertile patients and eighteen fertile males were selected randomly. The routine parameter analysis of semen was fulfilled by computer aided semen analysis(CASA).