Statistical Analysis of Current Oral Health Care and Dental Education Resources in China.

Objective: To collect information and statistical data regarding the current oral health care and dental education resources in China.

Methods: Electronic databases were searched and a literature review conducted. The homepages of relevant universities and colleges were visited to collect dental education information.

[Analysis of virulence-related properties of P. gingivalis clinical isolates].

Purpose: To analyze the relation of virulence properties and pathogenicity of Porphyromonas gingivalis (P.gingivals) isolated from Chinese patients.

Methods: Based on the previous analysis of virulence properties, investigations of pathogenicity properties, including the adhesion to host cells, gingipain activities, and resistance to host immune reaction were performed to analyze the diversity of pathogenic properties of these strains.

Prevalence and quantification of the uncommon Archaea phylotype Thermoplasmata in chronic periodontitis.

Objective: Chronic periodontitis is a chronic inflammatory disease of the periodontal tissues and is caused by invasion of certain types of bacteria and Archaea, with Methanobrevibacter oralis as the predominant archaeon. In this study, we investigated the prevalence and quantity of the newly discovered Archaea phylotype Thermoplasmata in patients with chronic periodontitis.

Methods: Subgingival plaque samples were obtained from 49 patients with chronic periodontitis and 45 periodontally healthy subjects.

Neutrophil-lymphocyte ratio predicts the prognosis of patients with hepatocellular carcinoma after liver transplantation.

Aim: To determine whether an elevated neutrophil-lymphocyte ratio (NLR) is negatively associated with tumor recurrence in patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) after liver transplantation (LT), and to determine the optimal predictive NLR cut-off value.

Methods: The data of HCC patients who had undergone LT came from the China Liver Transplant Registry database. We collected data from 326 liver cancer patients who had undergone LT at our medical center.

[A clinical study of osteotome sinus floor elevation and simultaneous implant placement in the periodontally compromised patients].

Purpose: To study the clinical effect of osteotome sinus floor elevation (OSFE) combined with simultaneous implant placement in the treatment of edentulous posterior maxilla subject to insufficient bone height in the periodontally compromised patients.

Methods: Forty-seven Straumanns implants were placed in the posterior maxilla in 35 patients with the procedure of OSFE. The final prostheses were restored after 3 to 6 months.

MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts.

Background: Although various microRNAs (miRNAs) regulate immune and inflammatory responses, the function of miRNAs in periodontitis has not been clearly illuminated. In this study, we measured miRNA-146 (miRNA-146a and miRNA-146b-5p) expression and explored its regulatory function in the inflammatory response in human gingival fibroblasts (HGFs).

Methods: miRNA-146a and miRNA-146b-5p expression was measured by performing real-time polymerase chain reaction in HGFs after Porphyromonas gingivalis (p.

[Virulent properties of Porphyromonas gingivalis clinical strains].

Purpose: To investigate the virulent properties of P. gingivalis clinical strains.

Methods: By using mouse abscess model (MAM), six P.

[Using DGGE to analyze bacteria community structure changes in subgingival plaque after periodontal initial therapy].

Purpose: To analyze bacteria community structure changes in subgingival plaque after initial therapy, and to provide experimental evidences for clinical decision.

Methods: Six patients with chronic periodontitis were chosen. Subgingival plaque samples, as well as clinical indexes, were collected at baseline and six weeks after initial therapy.

Role of p38 mitogen-activated protein kinase pathway in Porphyromonas gingivalis lipopolysaccharide-induced VCAM-1 expression in human aortic endothelial cells.

Background: Porphyromonas gingivalis (Pg) lipopolysaccharide (LPS) has been reported to induce the expression of vascular cell adhesion molecule-1 (VCAM-1) in vascular endothelial cells. This finding suggests the potential roles for Pg in the pathogenesis of atherosclerosis. However, the mechanism involved in Pg LPS-induced VCAM-1 production in endothelial cells remains unclear.

Comparison of microRNA profiles of human periodontal diseased and healthy gingival tissues.

MicroRNAs (miRNAs) have been demonstrated to play an important role in regulation of the immunoinflammatory response; however, the function of miRNAs in periodontal inflammation has not been investigated. The objective of this study was to explore the properties of miRNAs in periodontal inflammation by comparing miRNA profiles of inflamed and healthy gingival tissues. Gingival tissues were obtained from 10 periodontitis patients and 10 healthy subjects.

[The effect of periodontal initial therapy on chronic periodontitis and subgingival periodontal pathogen].

Purpose: To evaluate the effect of periodontal initial therapy on clinical parameters and subgingival periodontal pathogen in patients with chronic periodontitis.

Methods: One hundred and twenty patients with chronic periodontitis were included. Probing depth (PD), attachment loss (AL), plaque index (PLI) and gingival index (GI) were evaluated at baseline and after-initial therapy.