Publications by authors named "Da-Yi Chen"
Objective: To explore the preventive and therapeutic effects of Dahuang Zhechong Pill (DZP) on pulmonary fibrosis and the underlying mechanisms.
Methods: The first key rate-limiting enzyme hexokinase 2 (HK2) of glycolysis was silenced and over-expressed through small interfering RNA and lentivirus using lung fibroblast MRC-5 cell line, respectively. The cell viability, migration, invasion and proliferation were detected by cell counting kit-8, wound healing assay, transwell assay, and flow cytometry.
Neural Network-Based Strong Motion Prediction for On-Site Earthquake Early Warning.
Sensors (Basel)
January 2022
Developing on-site earthquake early warning systems has been a challenging problem because of time limitations and the amount of information that can be collected before the warning needs to be issued. A potential solution that could prevent severe disasters is to predict the potential strong motion using the initial P-wave signal and provide warnings before serious ground shaking starts. In practice, the accuracy of prediction is the most critical issue for earthquake early warning systems.
View Article and Find Full Text PDFDahuang Zhechong Pills Suppress Silicosis Fibrosis Progression via p38 MAPK/TGF-1/Smad Pathway .
Evid Based Complement Alternat Med
April 2021
Article Synopsis
- Dahuang Zhechong pills (DHZCP) are a traditional Chinese medicine that may help alleviate silicosis fibrosis by enhancing blood flow and reducing inflammation.
- The study investigated DHZCP's effects on MH-S cells exposed to SiO, showing that it improves cell survival, reduces inflammation markers, and regulates key signaling pathways.
- The findings suggest that DHZCP could be a beneficial treatment for silicosis by targeting inflammation and modifying specific cellular pathways.