Publications by authors named "Da-Wei Cui"

Aim: To determine the expression and function of epithelial membrane protein 1 (EMP1) in colorectal carcinoma.

Methods: Colorectal samples were taken from cancer lesions and adjacent normal tissue in colorectal cancer patients immediately after endoscopic biopsy. A portion of the sample was either fixed in 4% paraformaldehyde and embedded in paraffin for immunohistochemistry or stored in liquid nitrogen for Western blot.

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Article Synopsis
  • The study focused on the duration of viral shedding in stool samples of children with hand, foot, and mouth disease (HFMD) caused by enterovirus-71 (EV71) and coxsackievirus A16 (CoxA16), aiming to examine how this duration relates to illness severity.
  • A total of 113 confirmed cases were analyzed, with children split into distinct groups based on the virus type and severity of their condition, and stool samples were collected and tested for viral nucleic acids over several weeks.
  • Results showed that the median duration of stool viral shedding was similar for both EV71 and CoxA16 groups, but viral presence in stools decreased significantly over time, particularly in the severe illness subgroup of
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Objective: To investigate the molecular-epidemiologic characteristics and genotypes of human calicivirus (HuCVs) in acute diarrhea patients in Hangzhou from 2009 to 2010.

Methods: Epidemiologic data and fecal specimens were collected from patients with acute diarrhea. HuCVs of 920 specimens were detected by PCR.

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This work describes a general approach for preventing protein aggregation and surface adsorption by modifying proteins with β-cyclodextrins (βCD) via an efficient water-driven ligation. As compared to native unmodified proteins, the cyclodextrin-modified proteins (lysozyme and RNase A) exhibit significant reduction in aggregation, surface adsorption and increase in thermal stability. These results reveal a new chemistry for preventing protein aggregation and surface adsorption that is likely of different mechanisms than that by modifying proteins with poly(ethylene glycol).

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