[Association of CK20 expression with the progression, metastasis and prognosis of breast cancer].

Aim: To analyze the expression of CK20 in human breast cancer, and to evaluate the association between its expression and tumor's progression and prognosis.

Methods: 86 cases with breast cancer, 20 cases of benign tumor tissues were examined for the expression of CK20 by immunohistochemical staining.

Results: The positive rate of CK20 expression in breast cancer was 80.

HSP70 and mucin 5B: novel protein targets of N,N'-dinitrosopiperazine-induced nasopharyngeal tumorigenesis.

N,N'-Dinitrosopiperazine (DNP) induces nasopharyngeal carcinoma (NPC) and shows organ specificity to the nasopharyngeal epithelium. To investigate its mechanism, the rat NPC model was induced using DNP. Rat NPC and normal nasopharyngeal cells were obtained from the NPC model using laser capture.