Publications by authors named "Da-Lian Liang"
Bioorg Chem
September 2020
Article Synopsis
- - Five new cycloartane glycosides (named aspleniumside A-E) were found in the Asplenium ruprechtii Sa. Kurata plant, traditionally used in folk medicine for treating thromboangitis obliterans in East Asia.
- - The structure and stereo-chemistry of these compounds were examined using advanced NMR techniques, revealing a unique 24R configuration and indicating that the plant's growing environment affects its chemical makeup.
- - The new glycosides were tested for cytotoxicity against cancer cells (HL-60 and HepG2), showing promising results with potential applications in cancer treatment when compared to the standard drug sorafenib.
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Article Synopsis
- A new compound called camptoside was discovered along with three known compounds from the plant Camptosorus sibiricus.
- Their structures were identified using techniques like spectroscopic analysis, specifically 1D and 2D NMR data.
- The new compounds, particularly camptoside and the known compounds, showed potential in reducing nitric oxide production in certain macrophages, indicating possible anti-inflammatory properties.
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