Congenital Hypothyroidism Patients With Thyroid Hormone Receptor Variants Are Not Rare: A Systematic Review.

Background: Primary congenital hypothyroidism (CH) is a common endocrine and metabolic disease. Various genetic factors, including the thyroid hormone receptor (TSHR), play an important role in CH.

Aim: To explore the occurrence of pathogenic variants in CH.

[Artificial radial head replacement for the treatment of comminuted fractures of the radial head].

Objective: To assess the clinical effects of artificial radial head prosthesis replacement for the treatment of comminuted fracture of the radial head.

Methods: From June 2011 to June 2015, 25 patients with radial head comminuted fracture were treated with artificial radial head replacement, including 10 males and 15 females, ranging in age form 24 to 61 years old(mean, 40 years old). The functional recovery of the patients suffering from limb and elbow in different periods, the activity degree of the elbow joint and the function of the elbow in the latest follow-up were compared.