Publications by authors named "Da Zhi Tian"
Background: The most effective treatment for advanced cirrhosis and portal hypertension is liver transplantation (LT). However, splenomegaly and hypersplenism can persist even after LT in patients with massive splenomegaly.
Aim: To examine the feasibility of performing partial splenectomy during LT in patients with advanced cirrhosis combined with severe splenomegaly and hypersplenism.
Article Synopsis
- This study compared liver transplantation (LT) and liver resection (LR) in patients with hepatocellular carcinoma (HCC) who had portal vein tumor thrombus (PVTT) to determine which treatment was more effective and to find factors that influence prognosis.
- A total of 94 patients were analyzed, split evenly between the two treatment options, and their outcomes in terms of recurrence-free survival (RFS) and overall survival (OS) were assessed, particularly focusing on PVTT types I and II.
- Results indicated that LT generally offered a better prognosis than LR for patients with PVTT type I, especially those with high alpha-fetoprotein (AFP) levels, while no significant differences were found for patients with PVTT type
After half a century of development, auxiliary liver transplantation (ALT) technology gradually matured and major indications of ALT have been gradually expanded. This review summarized the history of ALT and introduced indications for ALT which including metabolic liver disease, fulminant hepatic failure, highly sensitized kidney transplantation, prevention of hepatic resection of small hepatic syndrome, etc.; at the same time, the hot issues related to ALT were discussed, including the regulation of hepatic portal blood flow of transplanted liver and residual liver, how to treat the graft liver and remaining liver on second stage.
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