The Network Construction of a New Byproduct-Free XLPE-Based Insulation Using a Click Chemistry-Type Reaction and a Theoretical Study of the Reaction Mechanism.

Cross-linked polyethylene (XLPE) is applied in most advanced high-voltage direct-current (HVDC) power cable insulations, which are produced via dicumyl peroxide (DCP) technology. The electrical conductivity of insulation material can be increased by cross-linking byproducts from the DCP process. Hence, currently much attention is being paid to a new process to produce cross-linking byproduct-free XLPE.

Synergistic Effect of CNT and N-Doped Graphene Foam on Improving the Corrosion Resistance of Zn Reinforced Epoxy Composite Coatings.

The synergistic effect of CNT and three-dimensional N-doped graphene foam (3DNG) on improving corrosion resistance of zinc-reinforced epoxy (ZRE) composite coatings was studied in this work. Although CNT itself was demonstrated to be effective to promote the anti-corrosion performance of the ZRE coating, the incorporation of additional 3DNG leads to further enhancement of its corrosion resistance under the synergistic effect of the hybrid carbon nanofillers with different dimensions. Both the content of the carbonaceous fillers and the ratio between them affected the performance of the coating.

Effects of Exogenous Spermidine on Seed Germination and Physiological Metabolism of Rice Under NaCl Stress.

Salt stress is one of the principal abiotic stresses limiting agricultural production and seriously inhibiting seed germination rates. This study selected the salt-tolerant rice variety HD961 and the salt-sensitive rice variety 9311 as experimental materials to investigate the physiological and metabolic effects of exogenous Spd seed priming on rice seeds and seedlings under NaCl stress. The experiment involved treating rice seeds with 0.

Comparative Analysis of Ca/Cation Antiporter Gene Family in and Enhanced Calcium Stress Tolerance via Heterologous Expression of RrCAX1a in Tobacco.

, a calciphilic species native to the mountainous regions of Southwest China, is renowned for its high vitamin C and bioactive components, making it valuable for culinary and medicinal uses. This species exhibits remarkable tolerance to the high-calcium conditions typical of karst terrains. However, the underlying mechanisms of this calcium resilience remain unclear.

Global Trends and Hotspots in Non-Targeted Screening of Water Pollution Research: Bibliometric and Visual Analysis.

Non-targeted screening (NTS) technology has been showing significant potential in identifying contaminants of emerging concern (CECs) in water and has attracted great attention in academia in recent years. It is a method that analyzes samples without pre-selecting substances, enabling the detection and identification of unknown compounds, which is crucial for environmental health and public protection. This study uses the Bibliometrix package in R 4.

Effects of Gene on Desiccation Resistance in .

, an opportunistic foodborne pathogen, has a strong resistance to osmotic stress and desiccation stress, but the current studies cannot elucidate this resistance mechanism absolutely. A mechanosensitive channel MscM was suspected of involving to desiccation resistance mechanism of To investigate the specific molecular mechanism, the mutant strain (Δ) was constructed using the homologous recombination method, and the complementary strain was obtained by gene complementation, followed by the analysis of the difference between the wild-type (WT), mutant, and complementary strains. Compared to the wild-type bacteria (WT), the inactivation rate of the Δ strain decreased by 15.

β,β-Difluoro Peroxides as Fluorinated C2-Building Blocks for the Construction of Functionalized Indolizines.

An effective method for the construction of functionalized indolizines has been developed in which β,β-difluoro peroxides act as novel C2-building blocks to implement [3+2] annulation with pyridinium ylides under base-mediated conditions. With this protocol, a broad range of multisubstituted indolizines were prepared in moderate to good yields under mild conditions, and many useful functional groups were tolerated.

Enhancing Mid-Term Strength and Microstructure of Fly Ash-Cement Paste Backfill with Silica Fume for Continuous Mining and Backfilling Operations.

Fly ash-cement composite backfill slurry, prepared by partially replacing cement with fly ash, has been demonstrated to effectively reduce the mine backfill costs and carbon emissions associated with cement production. However, the use of fly ash often results in insufficient early and medium-term strength of the backfill material. To address the demand for high medium-term strength in backfill materials under continuous mining and backfilling conditions, this study developed a silica fume-fly ash-cement composite backfill slurry.

Genetic Diversity and Differentiation of Silkworm () Local Germplasm Resources in China and Uzbekistan.

Silkworm () is an economically significant insect that produces silk and makes important contributions to the development of silk-producing countries. The genetic diversity and unique adaptive traits of silkworm germplasm resources form the foundation for breeding efforts. In various geographical regions, silkworm have developed distinct traits through long-term adaptive selection.

Nomogram Based on HRV for Predicting the Therapeutic Effects of Orthostatic Training in Children with Vasovagal Syncope.

Background: This study intended to find out whether the parameters of heart rate variability (HRV) can predict the treatment efficacy of orthostatic training among pediatric cases of vasovagal syncope (VVS).

Methods: Patients with VVS who underwent orthostatic training were retrospectively enrolled. Lasso and logistic regression were used to sift through variables and build the model, which is visualized using a nomogram.

Enhanced Wound Healing and Autogenesis Through Lentiviral Transfection of Adipose-Derived Stem Cells Combined with Dermal Substitute.

Background: Burns and chronic ulcers may cause severe skin loss, leading to critical health issues like shock, infection, sepsis, and multiple organ failure. Effective healing of full-thickness wounds may be challenging, with traditional methods facing limitations due to tissue shortage, infection, and lack of structural support.

Methods: This study explored the combined use of gene transfection and dermal substitutes to improve wound healing.

Multiorgan proteomic analysis of infected animal models predict potential host factors for chikungunya virus.

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that is primarily known for causing severe joint and muscle symptoms, but its pathological effects have extended beyond these tissues. In this study, we conducted a comprehensive proteomic analysis across various organs in rodent and nonhuman primate models to investigate CHIKV's impact on organs beyond joints and muscles and to identify key host factors involved in its pathogenesis. Our findings reveal significant species-specific similarities and differences in immune responses and metabolic regulation, with proteins like Interferon-Stimulated Gene 15 (ISG15) and Retinoic Acid-Inducible Gene I (RIG-I) playing crucial roles in the anti-CHIKV defense.

Insulator-donor electron wavefunction coupling in pseudo-bilayer organic solar cells achieving a certificated efficiency of 19.18.

The incorporation of polymeric insulators has led to notable achievements in the field of organic semiconductors. By altering the blending concentration, polymeric insulators exhibit extensive capabilities in regulating molecular configuration, film crystallinity, and mitigation of defect states. However, current research suggests that the improvement in such physical properties is primarily attributed to the enhancement of thin film morphology, an outcome that seems to be an inevitable consequence of incorporating insulators.

Data transmission delay compensation algorithm for interactive communication network of offshore oil field operation scene in bad weather.

A data transmission delay compensation algorithm for an interactive communication network of an offshore oil field operation scene in severe weather is proposed. To solve the problem of unstable microwave signals and a large amount of noise in the communication network caused by bad weather, the communication network signal denoising method based on Lagrange multiplier symplectic singular value mode decomposition is adopted, and the communication network data denoising process is realized through five steps; phase space reconstruction, symplectic geometric similarity transformation, grouping, diagonal averaging, and adaptive reconstruction. Simultaneously, the weak communication signal is compensated after being captured, that is, the characteristics of the weak signal are enhanced.

The impact of elevated CO on methanogen abundance and methane emissions in terrestrial ecosystems: A meta-analysis.

Methane (CH), one of the major greenhouse gases, plays a pivotal role in global climate change. Elevated CO concentration (eCO) increases soil carbon storage, which may provide a valuable material base for soil methanogenic microorganisms and stimulating their growth, thereby ultimately affecting CH emissions. Therefore, to comprehend the effect of eCO on CH emissions, we conducted a meta-analysis encompassing 398 datasets from 59 publications (total of 50 sample sites).

Enteric methane emissions, rumen fermentation, and milk composition of dairy cows fed 3-nitrooxypropanol and -malate supplements.

Twenty-four cows were used in a randomized complete block design. Cows were assigned to three groups: (1) Control, (2) 3-nitrooxypropanol (NOP) of 200 mg/kg feed dry matter (10% NOP), and (3) NOP × MAL (10% NOP at 200 mg/kg feed dry matter plus 99% -malate at 10 g/kg feed dry matter). Cows were fed for 10-wk.

New Insights into the Ion/Electron Transfer Mechanisms of LiMnO-Based Membrane Electrodes at Different Electron Fluxes.

Electrochemical Li extraction technology is a highly promising approach for Li extraction from salt lakes. To enhance its practical application, it is crucial to elucidate the ion/electron transfer mechanism under diverse process conditions particularly different electron fluxes. Different migration intermediate states demonstrate the distinct ion migration mechanisms inside the LiMnO lattice at different electron fluxes.

KIF4A on TGF-Β1/Smad3 Pathway: A Preliminary Investigation on the Proliferation and Immune Response in In-Vitro Cultured Breast Cancer Cells.

Aim: This study aims to explore the relevant biomarkers in breast cancer (BC).

Background: Kinesin family member 4A (KIF4A) is a member of the Kinesin 4 subfamily of kinesin-related proteins, which has already been investigated in diverse types of tumors.

Objective: Our current study aims to investigate the involvement of KIF4A in BC.

Efficient Functional Compensation Layer Integrated with HTL for Improved Stability and Performance in Perovskite Solar Cells.

Improving the interface characteristics between the hole-transport layer (HTL) and perovskite absorber layer is crucial for achieving maximum efficiency in inverted perovskite solar cells (PSCs). This paper presents an effective functional compensation layer (FCL) composed of benzothiophene derivatives, particularly 5-(trifluoromethyl)-1-benzothiophene-2-carboxylic acid (TFMBTA); this layer is introduced between the MeO-2PACz HTL and perovskite absorber layer to improve the interfacial characteristics between them. This FCL improves charge transfer, hole extraction, and perovskite deposition by improving the surface morphology of the HTL and optimizing the energy level alignment.

Comparative accuracy assessment of analog and virtual wax-up in prosthetic-driven planning and guided implant surgery: A retrospective cohort study.

Purpose: This retrospective cohort study evaluated the accuracy of analog versus virtual wax-ups in prosthetic-driven planning and guided surgery.

Methods: There were 73 patients with a single missing posterior tooth who underwent either an analog or virtual wax-up design following a prosthetic-driven concept. Intraoral scans of the final restoration were performed 1 year after completion of the restoration.

Assessment of the effect of non-ionic surfactant alkylphenol ethoxylates on the penetration of pesticides in fresh produce.

Understanding the penetration behaviour of pesticide active ingredient (AI) in the presence of adjuvants is important in managing application efficacy and minimizing residues. This study investigates the impact of non-ionic surfactant alkylphenol ethoxylates (APEOs) on the penetration of two pesticides, systemic thiabendazole and non-systemic phosmet, in apple and spinach. Surface-enhanced Raman Spectroscopy (SERS) was employed using two different detection methods, namely XZ depth mapping and XY area mapping, in conjunction with liquid Chromatography with tandem mass spectrometry (LC-MS/MS) to investigate the penetration of various pesticide formulations over time.

Nextflow4MS-DIAL: A Reproducible Nextflow-Based Workflow for Liquid Chromatography-Mass Spectrometry Metabolomics Data Processing.

Reproducibility in untargeted metabolomics data processing remains a significant challenge due to software limitations and the complex series of steps required. To address these issues, we developed Nextflow4MS-DIAL, a reproducible workflow for liquid chromatography-mass spectrometry (LC-MS) metabolomics data processing, validated with publicly available data from MetaboLights (MTBLS733). Nextflow4MS-DIAL automates LC-MS data processing to minimize human errors from manual data handling.

Cytotoxicity of Vanadium(IV) and Vanadium(V) on Caco-2 Cells: The Important Influence of Vanadium Speciation.

Exposure to vanadium (V) occurs through the ingestion of contaminated water, polluted soil, V-containing foods and medications, and the toxicity and absorption during the small intestine phase after oral ingestion play crucial roles in the ultimate health hazards posed by V. In this study, the human colon adenocarcinoma (Caco-2) cells were selected as an intestinal absorption model to investigate the uptake and cytotoxicity of vanadyl sulfate (VOSO) and sodium orthovanadate (NaVO). Our results confirmed the cytotoxic effects of V(IV) and V(V) and revealed a greater toxicity of V(IV) than V(V) towards Caco-2 cells.

Macrophage HERC6 Promotes NAFLD: Integrated Analyses of Mendelian Randomization and Single-Cell Transcriptome.

Aims And Objectives: This study aimed to explore the relationship between HERC6- associated immune response and Non-Alcoholic Fatty Liver Disease (NAFLD) and to screen drug candidates for novel treatments.

Materials And Methods: Mendelian Randomization (MR) was performed to test the relationship between a genetically predicted increase in HERC6 expression and the development of NAFLD. A single-cell RNA-seq profile of liver tissue with histological characteristics (GSE168933) was obtained.

Exploring transition states of protein conformational changes via out-of-distribution detection in the hyperspherical latent space.

Identifying transitional states is crucial for understanding protein conformational changes that underlie numerous biological processes. Markov state models (MSMs), built from Molecular Dynamics (MD) simulations, capture these dynamics through transitions among metastable conformational states, and have demonstrated success in studying protein conformational changes. However, MSMs face challenges in identifying transition states, as they partition MD conformations into discrete metastable states (or free energy minima), lacking description of transition states located at the free energy barriers.