Publications by authors named "DT Vo"

Medical diagnostics comprise recognizing patterns in images, tissue slides, and symptoms. Deep learning algorithms (DLs) are well suited to such tasks, but they are black boxes in various ways. To explain DL Computer-Aided Diagnostic (CAD) results and their accuracy to patients, to manage or drive the direction of future medical DLs, to make better decisions with CAD, etc.

View Article and Find Full Text PDF

Over the last decade, our knowledge of colorectal serrated polyps and lesions has significantly improved due to numerous studies on this group of precursor lesions. Serrated lesions were misleading as benign before 2010, but they are currently reclassified as precancerous lesions that contribute to 30% of colorectal cancer through the serrated neoplasia pathway. The World Health Organization updated the classification for serrated lesions and polyps of the colon and rectum in 2019, which is more concise and applicable in daily practice.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effectiveness of the JNET classification and magnified narrowband imaging (NBI) for evaluating colorectal polyps in Vietnam, focusing on how well it predicts their histology.
  • Conducted at the University Medical Center in Ho Chi Minh City, the research involved examining 1353 lesions in 739 patients and showed an overall accuracy of 86.9% in classifying lesions according to the JNET guidelines.
  • The findings suggest that while the JNET classification is highly effective for predicting the histology of colorectal polyps and guiding treatment decisions, it struggles with differentiating between malignant and benign neoplasia, emphasizing its role in reducing unnecessary surgeries.
View Article and Find Full Text PDF

Filling defects within the inferior vena cava (IVC) are common findings on computed tomography (CT); nevertheless, a majority of these defects are attributed to artifacts. The documentation pertaining to pseudothrombosis specifically affecting the infrarenal vena cava is notably insufficient in current literature. The aim of this study is to present a case demonstrating a blood-contrast level in the infrarenal vena cava, resembling an intraluminal filling defect.

View Article and Find Full Text PDF

Background/aims: Sessile-serrated lesions (SSLs) are challenging to detect due to their typically subtle appearance. The Workgroup serrAted polypS and Polyposis (WASP) classification was developed to diagnose SSLs endoscopically. This study aimed to evaluate the endoscopic characteristics of SSLs and the performance of the WASP classification in the Vietnamese population.

View Article and Find Full Text PDF

Background: Genetic factors and microbial imbalances play crucial roles in colorectal cancers (CRCs), yet the impact of infections on cancer initiation remains poorly understood. While bioinformatic approaches offer valuable insights, the rising incidence of CRCs creates a pressing need to precisely identify early CRC events. We constructed a network model to identify continuum states during CRC initiation spanning normal colonic tissue to pre-cancer lesions (adenomatous polyps) and examined the influence of microbes and host genetics.

View Article and Find Full Text PDF
Article Synopsis
  • - Portal cavernoma cholangiopathy (PCC) causes changes in the bile ducts and gallbladder due to portal cavernoma, leading to health complications.
  • - Acute acalculous cholecystitis (AAC) is a rare result of PCC, often misdiagnosed in patients experiencing right upper quadrant pain.
  • - This study presents a case of AAC caused by portal cavernoma, highlighting the importance of radiological findings and reviewing existing medical literature on the topic.
View Article and Find Full Text PDF

Standardizing image-data preparation practices to improve accuracy/consistency of AI diagnostic tools.

View Article and Find Full Text PDF
Article Synopsis
  • Millions of tons of plastics lead to microplastic particles entering the environment, contaminating water supplies, including bottled water.
  • Current technologies struggle to effectively remove microplastics from drinking water, raising concerns about their potential negative effects on human health.
  • There’s a need for comprehensive management strategies that combine current treatment technologies with approaches like life-cycle assessment and machine learning to tackle the microplastic issue.
View Article and Find Full Text PDF
Article Synopsis
  • Sessile serrated lesions (SSLs) are pre-cancerous growths in the colon that need to be detected and removed to prevent colorectal cancer; this study focuses on their prevalence and risk factors in Vietnam.
  • A group of 2489 patients underwent colonoscopy, revealing a 4.2% prevalence of SSLs, with key associated risk factors being age over 40, male sex, diabetes, and hypertension.
  • The study found that about 35.5% of SSLs had BRAF mutations, highlighting the genetic aspect of these lesions alongside their prevalence and associated risk factors.
View Article and Find Full Text PDF

Objectives: Our goal was to describe Invasive Meningococcal Disease (IMD) in Southern Vietnam over the last 10 years. We characterized 109 strains in Southern Vietnam isolated between 1980s to 2021, that were collected from IMD (n = 44), sexually transmitted infections (n = 2), and healthy carriage (n = 63).

Methods: IMD were confirmed by bacterial culture and/or real-time polymerase chain reaction at the national reference laboratory in Pasteur Institute of Ho Chi Minh City (PIHCM).

View Article and Find Full Text PDF

The seeds of Annona glabra L., an invasive plant in Vietnam, were first employed as a new biosorbent for the adsorption of methylene blue (MB) from aqueous media. The characterizations of the material using FT-IR, SEM, nitrogen adsorption-desorption analysis, and point of zero charge reveals that it possesses a rough and irregular surface, various polar functional groups, and pH of 5.

View Article and Find Full Text PDF

Objective: This study aimed to assess the incidence of early cancer therapy-related cardiac dysfunction (CTRCD) and the characteristics of left and right heart deformations during anthracycline chemotherapy.

Methods: We prospectively enrolled a cohort of 351 chemotherapy-naïve women with breast cancer and cardiovascular risk factors who were scheduled to receive anthracycline. The left ventricular ejection fraction (LVEF), left ventricular global longitudinal strain (LV-GLS) and right ventricular and left atrial longitudinal strains were evaluated using echocardiography at baseline, before every subsequent cycles and at 3 weeks after the final anthracycline dose.

View Article and Find Full Text PDF

We report on an outbreak of nongroupable Neisseria meningitidis-associated urethritis, primarily among men who have sex with men in southern Vietnam. Nearly 50% of N. meningitidis isolates were resistant to ciprofloxacin.

View Article and Find Full Text PDF

Background And Purpose: Radiation oncology protocols for single fraction radiosurgery recommend setting dosing criteria based on assumed risk of radionecrosis, which can be predicted by the 12 Gy normal brain volume (V12). In this study, we show that tumor surface area (SA) and a simple power-law model using only preplan variables can estimate and minimize radiosurgical toxicity.

Materials And Methods: A 245-patient cohort with 1217 brain metastases treated with single or distributed Gamma Knife sessions was reviewed retrospectively.

View Article and Find Full Text PDF

Objectives: Non-contrast computed tomography of the brain (NCCTB) is commonly used to detect intracranial pathology but is subject to interpretation errors. Machine learning can augment clinical decision-making and improve NCCTB scan interpretation. This retrospective detection accuracy study assessed the performance of radiologists assisted by a deep learning model and compared the standalone performance of the model with that of unassisted radiologists.

View Article and Find Full Text PDF

Introduction: This study aimed to elucidate the magnetic resonance (MR) characteristics of anal fistulas extending to the scrotum, and the applicable rules, and to correlate MR features with surgical findings.

Methods: We conducted a retrospective study in 150 consecutive patients with anal fistulas extending into the scrotum, who were diagnosed and underwent surgery at University Medical Center Ho Chi Minh City between January 2017 and April 2022. MR findings were evaluated and compared with surgical findings using Cohens kappa coefficient (k) with a 95% confidence interval.

View Article and Find Full Text PDF
Article Synopsis
  • This study looked at the trends and causes of pneumococcal meningitis in children under 5 in Southern Vietnam after the pentavalent vaccine was introduced in the Expanded Program on Immunization (EPI).
  • Over a 10-year period, 2560 suspected cases were reviewed, with only 158 (6.2%) confirmed as bacterial meningitis, mainly caused by a specific pathogen.
  • The research found a significant drop in pneumococcal meningitis due to vaccine serotypes, suggesting that policymakers should consider adding pneumococcal conjugate vaccines (PCVs) to immunization programs to better control this disease.
View Article and Find Full Text PDF

Pial arteriovenous fistula (PAVF) is a rare intracranial vascular lesion where direct communication exists between one or more pial arteries and a cerebral vein, without an intervening nidus and located in the subpial meningeal space. When the drainage of PAVF involves a dilated, but already formed vein of Galen (VOG), it should be distinguished from other vascular lesions located in this area, because their angio-architecture, natural history and treatment options are different. A 33-year-old female was admitted to our hospital with a history of new-onset generalized tonic-clonic seizures.

View Article and Find Full Text PDF

Cassia fistula seed-derived coagulant has been reported to exhibit high coagulating-flocculating activity, environmental friendliness, and cost-effectiveness for the wastewater treatment, especially of textile wastewater. For heavy metal removal, however, research focusing on evaluating the feasibility of this material is still limited. Therefore, this study reports jar-test experiments in which the Zn and Ni removal efficiency of C.

View Article and Find Full Text PDF

Purpose: To evaluate outcomes of adopting the Swenson-like technique in transanal pull-through for Hirschsprung disease (HD) at a children's institution in Southeast Asia.

Methods: A retrospective chart review was performed over 42 months at a safety-net pediatric hospital in Vietnam.

Results: From January 2019 to June 2022, the Swenson-like technique was implemented and performed on 139 patients (115 male, 24 female, mean age 6.

View Article and Find Full Text PDF

A late consequence of COVID-19, organizing pneumonia is characterized by significant imaging and pathological abnormalities. The goals of this study are to better understand these abnormalities. The use of corticoid continues to be the recommended course of treatment for COVID-19.

View Article and Find Full Text PDF