Critical interaction therapy: couples therapy in combat-related posttraumatic stress disorder.

There is a need for family therapy interventions that are specific to the conditions found in families of traumatized people such as combat veterans. In these families, the historically "real" event of the trauma often continues to exert influence on the family system despite collusive arrangements that serve to keep it hidden. In families of combat veterans, a situation develops whereby the veteran becomes triangulated with a dead buddy without the spouse's knowledge.

Comparison of methods for obtaining serum opacity factor from group A streptococci.

Streptococcal serum opacity factor (OF) is an important type-specific strain marker produced by certain serotypes of group A streptococci (GAS). The accurate determination of OF production and subsequent serotyping of a strain require a reliable method for extracting OF. Traditional OF extraction methods have utilized either culture supernatants or Lancefield HCl extracts.

Characterization of group A streptococci isolated in Kuala Lumpur, Malaysia.

T-agglutination patterns of 190 strains of group A streptococci isolated between January 1989 and December 1993 from body fluids (10), throat culture (56), pus (51) and skin lesions (73) were determined. Mucoid colonial morphology was exhibited by 6.3% (12/190) of the strains on initial isolation.

Outbreak of Shigella flexneri linked to salad prepared at a central commissary in Michigan.

In August 1992, the Michigan Department of Public Health was notified of a cluster of persons with Shigella flexneri infections, all of whom had eaten at different outlets of a single restaurant chain. The chain prepared many foods at a central kitchen. A matched case-control study to determine risk factors for illness among patrons of the restaurant chain was undertaken.

Dehydration and orthostatic vital signs in women with hyperemesis gravidarum.

Objectives: To assess the hydration status of women presenting to an ED with hyperemesis gravidarum and to determine whether clinically relevant changes in orthostatic vital signs occur.

Methods: A convenience sample of 23 pregnant women who had hyperemesis gravidarum, with each patient serving as her own control. The study took place in the ED observation unit of an urban teaching hospital.

Complementation of Saccharomyces cerevisiae strains containing fatty acid activation gene (FAA) deletions with a mammalian acyl-CoA synthetase.

Four unlinked fatty acid activation (FAA) genes encoding acyl-CoA synthetases have been identified in Saccharomyces cerevisiae and characterized by noting the phenotypes of isogenic strains containing all possible combinations of faa null alleles. None of these genes is required for vegetative growth when acyl-CoA production by the fatty acid synthetase (Fas) complex is active. When Fas is inhibited by cerulenin, exponentially growing cells are not viable on media containing a fermentable carbon source unless supplemented with fatty acids such as myristate, palmitate, or oleate.

Development of the spinous process of the second thoracic vertebra of the mouse in the late fetal and early postnatal period.

The bony spinous process of T2 in certain inbred strains of the mouse is variable in size or in some cases absent. The development of this process has been investigated in histological sections of CBA, C57BL and tk/tk mice between birth and 14 days. The spinous process is shown to be modified in shape and size late in development.

The therapeutic use of ritual and ceremony in the treatment of post-traumatic stress disorder.

The therapeutic purposes and effects of specially designed ceremonies in the treatment of persons with post-traumatic stress disorder are described. Ceremonies compartmentalize the review of the trauma, provide symbolic enactments of transformation of previously shattered relationships, and reestablish connections among family and with society in general. Four ceremonies used with Vietnam combat veterans are described which focus on the themes of separation from and return to the family, forgiveness of the living, and releasing the dead.

Case report: poorly differentiated carcinoma of unknown primary presenting as Trousseau's syndrome.

Two patients without clinical evidence of malignancy had idiopathic migratory thrombophlebitis. A clinical state consistent with Trousseau's syndrome prompted a work-up of each patient for occult cancer. In both individuals, computed tomography of the chest revealed a solitary mediastinal lymph node that, though inconspicuous, was evaluated further because of the clinical picture.

Expression of the wild-type p53 antioncogene induces guanine nucleotide-dependent stem cell division kinetics.

The predominant type of cell division in adult mammals is renewal growth. Renewing stem cells in somatic tissues undergo continuous asymmetric divisions. One new daughter cell retains the division potential of the original stem cell, while the other differentiates into a functional constituent of the tissue.

Saccharomyces cerevisiae contains four fatty acid activation (FAA) genes: an assessment of their role in regulating protein N-myristoylation and cellular lipid metabolism.

Saccharomyces cerevisiae has been used as a model for studying the regulation of protein N-myristoylation. MyristoylCoA:protein N-myristoyl-transferase (Nmt1p), is essential for vegetative growth and uses myristoylCoA as its substrate. MyristoylCoA is produced by the fatty acid synthetase (Fas) complex and by cellular acylCoA synthetases.

Suppressors of nmtl-181, a conditional lethal allele of the Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase gene, reveal proteins involved in regulating protein N-myristoylation.

Several essential Saccharomyces cerevisiae proteins require myristate to be covalently bound to their amino-terminal glycine for biological activity. Protein N-myristoylation is catalyzed by myristoyl-CoA:protein N-myristoyl-transferase, Nmt1p. nmt1-181 encodes a mutant enzyme with a Gly451-->Asp substitution.