Experimental evaluation of a GPU-based Monte Carlo dose calculation algorithm in the Monaco treatment planning system.

A new GPU-based Monte Carlo dose calculation algorithm (GPUMCD), devel-oped by the vendor Elekta for the Monaco treatment planning system (TPS), is capable of modeling dose for both a standard linear accelerator and an Elekta MRI linear accelerator. We have experimentally evaluated this algorithm for a standard Elekta Agility linear accelerator. A beam model was developed in the Monaco TPS (research version 5.

Dose heterogeneity correction for low-energy brachytherapy sources using dual-energy CT images.

Permanent seed implant brachytherapy is currently used for adjuvant radiotherapy of early stage prostate and breast cancer patients. The current standard for calculation of dose around brachytherapy sources is based on the AAPM TG-43 formalism, which generates the dose in a homogeneous water medium. Recently, AAPM TG-186 emphasized the importance of accounting for tissue heterogeneities.

SU-E-T-421: 6MV Radiation Small Field Dose: Off Axis and Penumbra Effects, a Study with Radiochromic Film.

Purpose: To accurately determine relative dose factor scaling, tissue depth relation, and penumbra details of small 6MV radiation fields with an emphasis on far-off-central-axis fields for various MLC designs -subject matter important in the context of SRS, FSRT, SBRT, and IMRT.

Methods: Radiochromic film designed for quantitative dosimetry, EBT3™ film (Ashland Inc.) can be reliably used as a relative dosimeter to within 1% accuracy if one controls for both film and flatbed scanner variation.

Intermediate energy photons (1 MV) to improve dose gradient, conformality, and homogeneity: potential benefits for small field intracranial radiosurgery.

A previously conceived and demonstrated principle of reducing penumbra for small radiosurgical dose fields is here now applied to a multiple beam arrangement in a stereotactic head phantom. In this work it is found that the fourfold reduction in radiological penumbra of small, single 1 MV x-ray fields translates to a more conformal, homogeneous dose distribution in the more complex beam arrangements. The film dosimetry is conducted with a high resolution digital microscope to quantify the sharp dose gradients.

Liquid embolisation material reduces the delivered radiation dose: a physical experiment.

Objective: To test a new hypothesis that the glue/contrast admixture used for embolisation reduces the dose delivered to AVMs using an experimental model.

Method: A model was created using a block of "solid water" (6 x 5 x 2 cm) with twelve wells of different depths. Different concentrations of the glue admixture (Enbucrilate + Lipiodol) were used.

Experimental measurement of radiological penumbra associated with intermediate energy x-rays (1 MV) and small radiosurgery field sizes.

Stereotactic radiosurgery is used to treat intracranial lesions with a high degree of accuracy. At the present time, x-ray energies at or above Co-60 gamma rays are used. Previous Monte Carlo simulations have demonstrated that intermediate energy x-ray photons or IEPs (defined to be photons in the energy range of 0.

Improvement of radiological penumbra using intermediate energy photons (IEP) for stereotactic radiosurgery.

Using efficient immobilization and dedicated beam collimation devices, stereotactic radiosurgery ensures highly conformal treatment of small tumours with limited microscopic extension. One contribution to normal tissue irradiation remains the radiological penumbra. This work aims at demonstrating that intermediate energy photons (IEP), above orthovoltage but below megavoltage, improve dose distribution for stereotactic radiosurgery for small irradiation field sizes due to a dramatic reduction of radiological penumbra.

Imaging of 1.0-mm-diameter radiopaque markers with megavoltage X-rays: an improved online imaging system.

Purpose: To improve an online portal imaging system such that implanted cylindrical gold markers of small diameter (no more than 1.0 mm) can be visualized. These small markers would make the implantation procedure much less traumatic for the patient than the large markers (1.

The precision and accuracy of noninvasive measurements of total body calcium in the rat.

It has been proposed that the adult castrated male rat may be used as a model of human postmenopausal osteoporosis. If such a model is valid then the total body calcium of castrated rats should progressively decrease compared with normal rats. To search for this age-related difference, it will be necessary to use a measurement technique with a precision which is small compared with the magnitude of the change to be detected.