Publications by authors named "D de Tonnerre"
Free-flap reconstruction methods in head-and-neck oncologic surgery: A CROSS practice survey of members of the French GETTEC Head-and-Neck Tumor Study Group.
Eur Ann Otorhinolaryngol Head Neck Dis
September 2024
Objective: To survey practices concerning the use of anticoagulants and antiplatelets in microvascular free-flap reconstruction following oncological surgery of the head and neck.
Methods: A survey of practices was carried out between September 2022 and March 2023. An online questionnaire was sent to members of the French GETTEC Head-and-Neck Tumor Study Group in all French centers practicing head-and-neck cancer surgery with reconstruction using microvascular free-flaps.
SimLife®: A New Dynamic Model for Head and Neck Surgical Oncology Simulation.
Otolaryngol Head Neck Surg
March 2024
The SimLife® model consists in a human cadaver dynamized by pulsatile vascularization. The objective was to evaluate the face, contents, and constructs validity of the SimLife® model in head and neck surgical oncology simulation. Head and neck surgical oncology simulation sessions on SimLife® models were organized with lateral neck dissection and total laryngectomy.
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- Sirolimus is a drug that may help regulate insulin levels in horses, showing promise for treating high insulin conditions in this species.
- A study on eight Standardbred geldings evaluated how sirolimus affects insulin responses and its pharmacokinetics, revealing significant reductions in insulin levels after administration.
- The results indicate that sirolimus can lower insulin response after glucose intake, suggesting potential clinical benefits, but more research is needed to fully understand its effects on insulin dynamics in horses, particularly those with insulin dysregulation.
Speech restoration with tracheoesophageal prosthesis after total laryngectomy: An observational study of vocal results, complications and quality of life.
Eur Ann Otorhinolaryngol Head Neck Dis
March 2022
Objectives: To study voice prosthesis survival, complications, efficacy and impact on quality of life.
Methods: A single-center observational study was performed in patients treated for squamous cell carcinoma of the larynx or hypopharynx by total (pharyngo)-laryngectomy between 2010 and 2015. Study data comprised: maximum phonation time (sec), number of and reasons for prosthesis exchanges (leakage through or around the prosthesis, expulsion or inclusion of the prosthesis), plus 2 quality of life questionnaires (QLQ-C30, QLQ-H&N35) and the Voice Handicap Inventory (VHI 30).