Gestational Diabetes Mellitus Does Not Change the Pharmacokinetics and Transplacental Distribution of Fluoxetine and Norfluoxetine Enantiomers.

: Fluoxetine (FLX) is the inhibitor of serotonin reuptake most prescribed in pregnant women with depression. This study evaluates the influence of gestational diabetes mellitus (GDM) on the enantioselective pharmacokinetics and transplacental distribution of FLX and its metabolite norfluoxetine (norFLX). : Ten pregnant women diagnosed with GDM (GDM group) were investigated in the third trimester of gestation after they achieved good glycemic control.

Advances in the estimation of body fat percentage using an artificial intelligence 2D-photo method.

There is a growing need to evaluate the agreement between the field methods and integrate artificial intelligence (AI) using two-dimensional (2D) photos for enhanced real-world analysis. This study evaluated the agreement between AI-2D photos and the clinical reference method, dual-energy X-ray absorptiometry (DXA) to estimate the body fat percentage (BFP). Other methods were also investigated, including skinfolds, A-mode ultrasound, and bioelectrical impedance analysis (BIA).

Concurrent validity of skin-based motion capture systems in measuring dynamic lumbar intervertebral angles.

Spine kinematics are commonly measured by external sensors such as motion capture and accelerometers. However, these skin-based measures cannot directly capture intervertebral motion of the lumbar spine. To date, research in this area has focused on the estimation of intervertebral kinematics using static trials but no study has analyzed agreement throughout the dynamic range of motion.

Efficiency of four trap types and human landing catch in the sampling of Mansonia (Diptera, Culicidae) in Porto Velho, Rondônia, Brazil.

Entomological surveillance plays a crucial role in designing and implementing mosquito control measures. In this context, developing more effective collection strategies is essential to accurately estimate the entomological parameters necessary for effective control. In this study, we investigated the effectiveness of four traps: CDC light trap, MosqTent, BG-Sentinel, and SkeeterVac, compared to human landing catch (HLC) in the collection of Mansonia mosquitoes, known to cause discomfort to riverside populations along the Madeira River in the District of Jaci Paraná, Porto Velho, in Rondônia state, Brazil.

Relationship between severe hypoglycemia or impaired awareness of hypoglycemia and diabetes-related health status, global cognition and executive functions in adults with type 1 diabetes without severe anxiety or depression.

Aims: To explore the relationship between impaired awareness of hypoglycemia (IAH) or severe hypoglycemia (SH), and health status and cognition in adults with type 1 diabetes (T1D).

Methods: T1D adults attending a tertiary diabetes service were recruited into this cross-sectional study. People screening positive for severe anxiety or depression were not included.