Publications by authors named "D Zucca"
Introduction: SRS for the treatment of limited brain metastases (BM) is widely accepted, but there are still limitations in the management of numerous BM. Frameless single-isocenter multitarget SRS is a novel technique that allows for rapid treatment delivery to multiple BM. We report our preliminary clinical, dosimetric, and patient´s shifts outcomes with this technique.
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- Recurrent high-grade gliomas pose a treatment challenge; this study evaluates the effectiveness and tolerability of Hypofractionated Stereotactic Radiation (HFSRT) in re-irradiation.
- A retrospective analysis of 52 patients treated between 2011 and 2021 showed median overall survival of 12 months, with re-irradiation doses differing among patients.
- The treatment was mostly well-tolerated, with minimal severe side effects, indicating HFSRT as a promising option for managing these tumors.
Purpose: This study aims to evaluate the positioning correction extracted from Intra-fraction Cone Beam (IF-CBCT) images obtained during Stereotactic Body Radiotherapy (SBRT) treatments, and to assess whether its magnitude justifies its acquisition. In addition, the results obtained in lung, liver, and pancreas SBRTs with two deep inspiration breath-hold systems (DIBH), and for prostate with/without ultrasound (US) monitoring were compared.
Methods: 1449 treatments, performed with two linear accelerators (LINACs) were retrospectively analyzed.
Purpose: This study aims to investigate lattice radiotherapy (LRT) for bulky tumor in 10 patients, analyzing geometrical and dosimetrical parameters and correlations among variables.
Methods: Patients were prescribed a single-fraction of 18 Gy to 50 % of each spherical vertex (1.5 cm diameter).
Purpose: Moderate hypofractionated radiotherapy is the standard of care for all patients with breast cancer, irrespective of stage or prior treatments. While extreme hypofractionation is accepted for early-stage tumours, its application in irradiating locoregional lymph nodes remains controversial.
Materials And Methods: A prospective registry analysis from July 2020 to September 2023 included 276 patients with early-stage breast cancer treated with one-week ultra-hypofractionation (UHF) at 26 Gy in 5 fractions on the whole breast (58.