Publications by authors named "D Zanon"
Alternating hemiplegia of childhood (AHC) is a rare neurological disorder that usually manifests before 18 months of age and is characterized by recurrent, alternating episodes of hemiparesis with variable frequency and can last from a few minutes to several days. We present a case of AHC in a little girl carrying a sporadic mutation in the ATP1A3 gene (p.Glu815Lys) refractory to flunarizine and non-compliant to topiramate due to adverse effects treated with oral compound of adenosine-5'-triphosphate (ATP) capsules.
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- Pediatric patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) face risks related to their nutritional status, specifically body mass index (BMI), which affects transplantation success.
- A study analyzed BMI data from patients treated between 2003 and 2023 and found that underweight patients had significantly lower survival rates and higher complications compared to those with normal or higher BMI.
- The research emphasizes the need for regular nutritional assessment before and after transplant to improve outcomes, suggesting that BMI should be closely monitored to manage risks effectively.
Article Synopsis
- * A method called HPLC-UV was employed to assess the chemical stability, confirming that most storage conditions maintained the medication's concentration within acceptable limits.
- * The study found that glycopyrrolate remains stable for at least 210 days at room temperature or 4 °C in different types of containers, except for glass at 45 °C, ensuring safety and quality for pediatric use.