Introduction: In the structure of illnesses connected with malignant tumors (MT) among women's population of Ukraine breast cancer (BC) holds a leading position and was at the level of 19.3% in 2014.
The Aim: The aim of research is a comparative analysis of BC illnesses among women's population in regional centers of Prydniprovsk-Donetsk which is an intensive industrial zone (Dnipropetrovsk city) and Transcarpathian region, clean natural area (Uzhgorod city).
Aim: To determine the receptor status of tumors as prognostic factor in development of bilateral breast cancer (BBC) and factor of prognosis of disease.
Patients And Methods: 272 cases of BBC during the period from 1995 to 2011 in different oncological institutions of Ukraine have been analyzed.
Results: Patients with metachronous BBC with positive status of hormone receptors (HR) of tumors have significantly better indices of overall and progression-free survival (three-years - 95%, five-years - 72%), than patients with HR-negative status (among them nobody has survived over 5 years).
In a period of catastrophic flood in 1998 and 2001 yrs there was noted the enhancement of general quantity of patients with gastroduodenal ulcer disease as well as with complicated course, including gastroduodenal ulcer perforation. In the period of flood in Zakarpattya in 2001 the quantity of patients, who were admitted to hospital, to Tyachiv and Vinogradiv central district hospitals in particular, too late, was enhanced as twice. In conditions of extreme situation it is expedient to conduct prophylactic treatment of patients, who are staying under the dispensary observation for gastroduodenal ulcer disease.
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