Unravelling the influence of structure on the optical properties of a pair of aza-BODIPY isomers and their application in photodynamic therapy.

A pair of aza-BODIPY isomers, 1,7-di--butyl-3,5-dinaphthyl (Nap-BDP) and 1,7-dinaphthyl-3,5-di--butyl (revNap-BDP), were prepared in this study. According to the single crystal X-ray analysis, Nap-BDP exhibited an orthogonal structure. Owing to the difference in orthogonality and -Bu rotation between Nap-BDP and revNap-BDP, their spectral performances, including maximum absorption and emission, full width at half maximum, fluorescence quantum yield, photostability, singlet oxygen generation and photothermal conversion efficiency, were obviously different.

Rapid and reversible sodium-ion cathode materials for NASICON NaMnTiPBO achieved through Boron-substitution.

NaMnTi(PO) is a promising sodium-ion cathode material due to its relatively high specific capacity, excellent thermodynamic stability and low cost. However, unfavorable electron conductivity and slow kinetics limit its practical application. Here, a strategy of hetero and multivalent anion substitution is proposed to achieve high-rate performance and good capacity retention.

Compound FLZ attenuates neuroinflammation through inhibiting Src/PTEN/Akt signaling pathway.

Compound FLZ has neuroprotective effects on Parkinson's disease (PD), while the precise mechanism remains unclear. In this study, we found that FLZ decreased PTEN/Akt activity in LPS-challenged BV2 cells. Neuroinflammatory responses suppressed by FLZ were abolished when PTEN or Src was inhibited.

infection specifically suppresses the expression of a host lncRNA to facilitate parasite propagation by modulating host cell mitochondrial function and autophagy.

is one of the most common pathogens causing reproductive failure in ruminants (e.g., cattle and goats) worldwide.

Development of a Rapid Visual Detection Assay for Duck Tembusu Virus Using RT-LAMP-CRISPR/Cas12a.

Duck Tembusu virus (DTMUV) is an emerging flavivirus that has inflicted significant economic losses on China's poultry industry. Rapid and accurate detection of DTMUV is crucial for effective prevention and control measures. In this study, we developed a novel, rapid visual detection assay that combines reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) with the CRISPR/Cas12a system for on-site detection of DTMUV.