Publications by authors named "D Y Charpentier"

Article Synopsis
  • Myo-inositol is elevated in patients with heart failure (HF), particularly in those with heart failure with preserved ejection fraction (HFpEF), and is associated with negative clinical outcomes.
  • The study measured plasmatic myo-inositol levels in large cohorts from Belgium and Canada, revealing significant increases in HF patients compared to those without.
  • Elevated myo-inositol levels correlate with worsening kidney function and cardiac markers, suggesting a potential role in the development and progression of HFpEF.
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Objectives: Since 2018, four establishments in Quebec have been instrumental in implementing the PAROLE-Onco program, which introduced accompanying patients (APs) into healthcare teams to improve cancer patients' experience. APs are patient advisors who have acquired specific experiential knowledge related to living with cancer, using services, and interacting with healthcare professionals. They are therefore in a unique and reliable position to be able to provide emotional, informational, cognitive and navigational support to patients who are dealing with cancer.

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Article Synopsis
  • The study investigates the link between gut microbiome composition and chemoradiation-related toxicities, particularly mucositis, in patients with locally advanced head and neck squamous cell cancer (HNSCC).
  • It involved analyzing stool samples from 52 patients before treatment and tracking their health outcomes, including the severity of mucositis and its impact on survival rates.
  • Results indicated that specific gut bacteria were associated with varying degrees of mucositis severity, suggesting the microbiome could serve as a potential biomarker for predicting adverse effects of treatment. *
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Objectives: Delays in treatment time intervals have been associated with overall survival in oral cavity squamous cell carcinoma (OCSCC). The aim of this study was to identify bottlenecks leading to prolonged treatment intervals.

Material And Methods: A retrospective analysis was conducted using a cohort of OCSCC patients who underwent surgery and adjuvant radiation therapy.

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