The study aimed to evaluate the antithrombotic action of pulp oil (AAPO) in natura, in an in vitro experimental model. AAPO was obtained by solvent extraction, and its chemical characterization was performed by gas chromatography coupled to a mass spectrometer (GC-MS). In vitro toxicity was evaluated with the Trypan Blue exclusion test and in vivo by the model.
View Article and Find Full Text PDFCoronavirus disease (COVID-19) is an acute respiratory disease caused by the new coronavirus (SARS-CoV-2) that has spread throughout the world causing millions of deaths. COVID-19 promotes excessive release of pro-inflammatory cytokines leading to acute lung injury and death. Reactive oxygen species (ROS) and oxidative stress (OS) may also play a role in the pathophysiology of COVID-19.
View Article and Find Full Text PDFIntroduction: Oxidative stress (OS) occurs in cystic fibrosis (CF).
Objective: The objective of this work is to evaluate the influence of bacterial infection on biomarkers of OS (catalase [CAT], glutathione peroxidade [GPx], reduced glutathione [GSH]), markers of oxidative damage (protein carbonyls [PC], thiobarbituric acid reactive substances [TBARS]), together with the nutritional status and lung function in children with CF.
Methods: Cross-sectional study including CF group (CFG, n = 55) and control group (CG, n = 31), median age: 3.
fruits are rich in monounsaturated fatty acid, carotene, tocopherol, and other antioxidant compounds. The aim of our study was to investigate and compare the protective effects of pulp oil and microencapsulated pulp oil on brain oxidative damage induced by chronic restraint stress (CRS) in rats (cortex, hippocampus, and striatum). Thirty-six Wistar rats were divided into six treatment groups: C, P, and M groups received 1 L/g of body weight of distilled water, pulp oil, and pulp oil microcapsules by daily gavage, respectively.
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