Publications by authors named "D Westermann"

Aims: This study aimed to investigate incidence and predictors of weaning failure and in-hospital death after successful weaning from veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in patients with cardiogenic shock (CS).

Methods And Results: Overall, 685 patients with CS treated with VA-ECMO from 23 tertiary care centres in 7 countries were analysed (median age 57 [interquartile range 49-66] years, 542 [79.1%] male, median lactate 7.

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: To validate the automated quantification of cardiac chamber volumes and myocardial mass on non-contrast chest CT using cardiac MR (CMR) as a reference. : We retrospectively included 53 consecutive patients who received non-contrast chest CT and CMR within three weeks. A deep learning model created cardiac segmentations on axial soft-tissue reconstructions from CT, covering all four cardiac chambers and the left ventricular myocardium.

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Background: The clinical outcome and fluid balance of patients with veno-arterial extracorporeal membrane oxygenation (VA ECMO) or after extracorporeal cardiopulmonary resuscitation (eCPR) may be improved by addressing the high fluid demand with an early albumin administration.

Methods: In this prospective observational study, patients supported with VA ECMO or eCPR received early albumin administration (25 g/L) to prime the VA ECMO system. These patients were compared to patients who received a regimen based solely on balanced crystalloids (crystalloid group) or a regimen based on a 1:4 volume mixture of albumin (10 g/L) and balanced crystalloids (albumin group).

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Article Synopsis
  • The study investigates whether different sedation depths during targeted temperature management (TTM) can affect neurological outcomes in post-cardiac arrest patients.
  • It analyzed data from a medical ICU over several years, comparing patients sedated to a RASS-target of -5 versus -4, focusing on favorable neurological outcomes defined as a Cerebral Performance Category (CPC) score of 1 or 2.
  • The results suggest that lighter sedation (RASS-target -4) is linked to better neurological outcomes and 30-day survival rates compared to deeper sedation (RASS-target -5), indicating a need for further research in this area.
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