Publications by authors named "D Wessels"

Article Synopsis
  • Alzheimer's disease is a leading cause of dementia, and recent research shows that immune cells outside the brain may play a role in the disease, but we don’t fully understand how yet.
  • In a study, scientists compared immune cell changes in Alzheimer's patients with mild cognitive issues to healthy people using advanced technology to see these cells better.
  • They discovered specific types of immune cells were linked to brain issues and memory problems, and some immunity changes were influenced by a gene called APOE ε4, showing it’s important to study these immune changes further.
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Aims: Understanding of the pathophysiology of progressive heart failure (HF) in patients with heart failure with preserved ejection fraction (HFpEF) is incomplete. We sought to identify factors differentially associated with risk of progressive HF death and hospitalization in patients with HFpEF compared with patients with HF and reduced ejection fraction (HFrEF).

Methods And Results: Prospective cohort study of patients newly referred to secondary care with suspicion of HF, based on symptoms and signs of HF and elevated natriuretic peptides (NP), followed up for a minimum of 6 years.

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Oats ( L.) are well known for their nutritional properties but are susceptible to the growth of different fungi resulting in mycotoxin contamination of harvested oats. In this study, oat samples from harvest years 2011 to 2017 were preselected for their suitability as milling oats for food purposes with DON contents below 1750 µg/kg.

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Cancer cells from cell lines and tumor biopsy tissue undergo aggregation and aggregate coalescence when dispersed in a 3D Matrigel™ matrix. Coalescence is a dynamic process mediated by a subset of cells within the population of cancer cells. In contrast, non-tumorigenic cells from normal cell lines and normal tissues do not aggregate or coalesce, nor do they possess the motile cell types that orchestrate coalescence of cancer cells.

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During induced differentiation, the process often involves a commitment event, after which induced cells, when returned to noninducing conditions, continue to differentiate. The commitment event is rarely identified. Candida albicans differentiates from the white to opaque phenotype, a prerequisite for mating and a process accompanying colonization of the lower gastrointestinal tract and skin.

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