Publications by authors named "D Wen Lou"

FeOOH with excellent catalytic properties for oxygen evolution and also considered to be a true active site has attracted great interest in recent years. However, the intrinsic low conductivity limits its catalytic performance. Herein, a one-dimensional core-shell NiMoO/FeOOH heterojunction with high OER activity and stability was developed.

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Introduction: This study aims to investigate the relationship between blood-based pathologies and established risk factors for cognitive decline in the community-based population of Chongqing, a region with significant aging.

Methods: A total of 26,554 residents aged 50 years and older were recruited. Multinomial logistic regression models were applied to assess the risk factors of cognition levels.

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Article Synopsis
  • Single-cell RNA sequencing (scRNA-seq) is a powerful technique that helps identify rare cells, discover new cellular subclusters, and study gene expression in individual cells, revealing shifts in cellular phenotypes and subtype heterogeneities.* -
  • Since its introduction in 2009, scRNA-seq has evolved with advancements like cell-specific barcodes and droplet-based systems, despite challenges such as cellular stress during sample preparation.* -
  • Recent innovations in spatial transcriptomics enhance understanding of cellular organization by preserving the spatial context of gene activity, leading to promising future research directions that combine this data with other omics for deeper insights.*
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  • Chemoenzymatic dynamic kinetic resolution (DKR) combines a metal racemization catalyst and an enzyme to effectively convert racemic compounds into enantiopure products, with compatibility between the two catalysts as a significant challenge.
  • The study introduces a reliable ligand that enhances the coordination between the metal and the ligand, enabling better performance in the DKR process.
  • An efficient DKR method was developed using a copper catalyst and lipase LPL-311-Celite, successfully producing high yields of chiral BINOLs and other functionalized chiral biaryls, with a proposed mechanism involving a radical-anion intermediate facilitating the reaction.
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The crystallization of organic polymers is often hindered by chiral units, hence resulting in chiral organic polymers typically existing as amorphous or partially crystalline phases such as natural rubber and cellulose. Similarly, as an emerging crystalline chiral polymer, chiral covalent organic frameworks (COFs) also inevitably face a delicate balance between chiral units and crystallization, limiting their production and applications in separation, catalysis, and optics. Here, we present a general strategy for producing a series of conformational chiral COFs with high crystallinity through breaking the meso conformation of achiral COFs.

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