Therapeutic value of Ginkgo biloba in reducing symptoms of decline in mental function.

The Chinese tree Ginkgo biloba or "maiden hair tree" is extensively cultivated for the exploitation of the medicinal properties of its leaves. From these, a well-defined extract designated "EGb 761" has been developed, which was commercialized initially as Tanakan, Tebonin and Rokin; a similar product, Kaveri (LI 3170), also exists. The major therapeutic applications for these products are "cerebral insufficiency", other cerebral disorders, neurosensory problems and peripheral circulatory disturbances.

Actions of terfenadine and cimetidine on histamine wheal formation.

1. A Latin square design was used to compare the effects of four masked oral drugs, placebo, cimetidine, terfenadine and cimetidine plus terfenadine, at single standard doses against histamine injected at concentrations of 0.3 mM and 0.

The basis of the histamine assay in human skin: II. Wheal formation.

1. Subepidermal injection of histamine solutions in isotonic saline in four subjects evoked whealing after a mean delay of 2.6 min, this estimate being derived by regression modelling.

The basis of the histamine assay in skin.

1. The assay of wheal response to histamine injected sub-epidermally has been reviewed. Several discrepant claims were found in earlier work.