Zinc as a Mechanism-Based Strategy for Mitigation of Metals Toxicity.

Purpose Of Review: Zinc is an essential micronutrient with a myriad of key roles in human health. This review summarizes mechanistic data supporting the protective effects of zinc on metal toxicity and discusses the framework for an interventional clinical trial of zinc supplementation within a metal exposed Native American community.

Recent Findings: Many metals have common underlying mechanisms of toxicity that contribute to adverse human health effects.

Performance of transesophageal echocardiography probe at temperature monitoring during simulated hypothermia and rewarming.

Objective: To determine whether a transesophageal echocardiography (TEE) probe can accurately measure temperature and be used to monitor temperature changes over time without overheating in an experimental model of hypothermia and rewarming.

Methods: A 6L water bath was heated with a sous vide immersion circulator to 24C, 28C, 32C and 36C to simulate severe hypothermia, moderate hypothermia, mild hypothermia, and normothermia. A TEE probe, esophageal temperature probe, and bladder temperature probe were used to measure temperature.

Post-COVID-19 Pandemic Restrictions: Follow-Up on Changes Within Canadian Academic and Fieldwork Curricula.

COVID-19 pandemic restrictions necessitated curricular modifications in Canadian occupational therapy education. Documentation and reflection on temporary or permanent curriculum modifications and their perceived impact on student learning and outcomes is critical. To explore and compare reported curricula changes (academic and fieldwork) during restricted and post-restricted delivery periods together with the perceived impact on learners.

A descriptive examination of rurality in the Environmental influences on Child Health Outcomes Cohort: Implications, illustrations, and future directions.

Purpose: The Environmental influences on Child Health Outcomes (ECHO) Cohort has enrolled over 60,000 children to examine how early environmental factors (broadly defined) are associated with key child health outcomes. The ECHO Cohort may be well-positioned to contribute to our understanding of rural environments and contexts, which has implications for rural health disparities research. The present study examined the outcome of child obesity to not only illustrate the suitability of ECHO Cohort data for these purposes but also determine how various definitions of rural and urban populations impact the presentation of findings and their interpretation.

Assessment of field performance and bruchid resistance during seed storage of a genetically modified cowpea expressing the alpha-amylase inhibitor 1 protein from common bean.

Introduction: The cowpea weevil, Fab., is the most economically important storage pest of cowpeas, causing up to 100 percent grain losses within six months of storage. To sustainably resist weevil damage, the cowpea cultivar IT86D-1010 was genetically modified via -mediated transformation to produce event CSI-32, which expresses the kidney bean alpha-amylase inhibitor 1 (αAI-1) protein exclusively in the seed, providing suppression of weevil development.