Publications by authors named "D W Kikuchi"

While veterinary pharmacy is common overseas, it has yet to gain traction in Japan. To clarify the actual situation in Japan, two surveys were conducted, targeting 4017 facilities (2000 pharmacies/drug stores, 2000 veterinary medical facilities, and 17 university-affiliated veterinary hospitals). We received 324 responses from pharmacy staff and 217 from veterinary hospital staff.

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Background And Aim: Endoscopic submucosal dissection (ESD) is an acceptable treatment for superficial esophageal squamous cell carcinoma (ESCC) even in elderly patients. However, studies on the prognostic factors in very elderly patients are limited. Therefore, we aimed to explore the prognostic factors affecting overall survival (OS) in patients aged ≥ 80 with superficial ESCC who underwent ESD.

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Patient-reported outcomes (PROs) are becoming pivotal in managing gastroesophageal reflux disease (GERD). Current Japanese guidelines for GERD recommend vonoprazan (VPZ) as a treatment option for mild reflux esophagitis (RE). However, it has been hypothesized that 4 weeks of VPZ 20 mg is not always necessary for mild RE if the treatment outcome is based on patient symptoms.

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Article Synopsis
  • HIV-associated cardiovascular disease (CVD) is becoming more common, but the reasons for this increased risk in people living with HIV (PWH) are not well understood, particularly regarding lipoprotein(a) [Lp(a)].
  • A study involving 65 PWH and 52 controls found that Lp(a) levels were significantly higher in PWH, and they showed lower coronary endothelial function (CEF) as measured by cardiac imaging.
  • The study concluded that elevated Lp(a) in PWH is linked to impaired CEF, suggesting that Lp(a) might contribute to the increased cardiovascular risk in this population.
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In recent years, cases of diverticular bleeding have become more common. Although identifying the bleeding diverticulum is difficult, it is even more difficult to identify the exposed blood vessels in the bleeding diverticulum. We experienced a case in which we succeeded in directly observing the exposed blood vessels of a sigmoid colon diverticulum using the ultrathin endoscope.

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