Bioinformatics and Computationally Supported Redesign of Aspartase for β-Alanine Synthesis by Acrylic Acid Hydroamination.

Aspartate ammonia lyases catalyze the reversible amination of fumarate to l-aspartate. Recent studies demonstrate that the thermostable enzyme from sp. YM55-1 (AspB) can be engineered for the enantioselective production of substituted β-amino acids.

Understanding the determinants and outcomes of education in pulmonary rehabilitation: moving towards person-centered care.

Topic Importance: Education and psychosocial support are essential components of pulmonary rehabilitation (PR). However, the delivery of education often follows a one-size-fits-all approach, with individual factors that influence learning rarely considered. Moreover, education-related outcomes are frequently overlooked in PR assessments, and inconsistent use of these outcomes has limited our understanding of the impact of education on people with chronic respiratory diseases.

Koro (Genital Retraction): Early Mention in 1849 by Carl Wilhelm Maurus Schmidtmüller and Early Psychiatric Verdict in 1883 by E.A. Aldridge.

This short historical note dates the earliest ethnomedical reference to koro back to the 1840s (about a half-century earlier than universally presumed), and the earliest ethnopsychiatric reference to 1883 (over a decade earlier than universally presumed).