Publications by authors named "D W Hedley"
Self-injurious thoughts and behaviors are high among autistic youth, yet research most often relies on caregiver reports and does not include youth perspectives. Relatedly, specific characteristics of self-injurious thoughts and behaviors (e.g.
View Article and Find Full Text PDFThe world in 2024 faces numerous interlinked crises, including climate change and water shortages, rising geopolitical tensions, and a new awareness of the risks of pandemics. These crises reverse decades of incremental development progress and humanity's aspirations embodied in the 2030 Agenda for Sustainable Development, necessitating a more active and collaborative participation of development stakeholders. The magnitude of challenges points to the need for transformational approaches to releasing the potential of stakeholders, which requires building on and extending beyond current best practices in participation and capacity strengthening.
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- Long-term survival rates after lung transplantation are hindered by chronic lung allograft dysfunction (CLAD), primarily characterized by two conditions: bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS).
- The study utilized imaging mass cytometry (IMC) to analyze lung samples from BOS, RAS, and control groups, identifying 50 distinct immune and non-immune cell clusters with notable differences.
- Findings revealed that CLAD lungs had fewer club cells, a higher presence of Ki67-high basal cells near memory T cells in RAS, and an increased occurrence of memory CD8 T cells in CLAD lungs, along with more regulatory T cells in RAS, highlighting IMC