Mapping quantitative trait loci regions associated with Marek's disease on chicken autosomes by means of selective DNA pooling.

Marek's Disease (MD), which can result in neurological damage and tumour formation, has large effects on the economy and animal welfare of the poultry industry worldwide. Previously, we mapped autosomal MD QTL regions (QTLRs) by individual genotyping of an F population from a full-sib advanced intercross line. We further mapped MD QTLRs on the chicken Z chromosome (GGZ) using the same F population, and by selective DNA pooling (SDP) of 8 elite egg production lines.

The influence of circulating cold water cryotherapy with or without intermittent pneumatic compression on shoulder joint position sense (JPS) in recreationally active adults: A randomized crossover trial.

Objectives: Cryotherapy is a widely used intervention in sports settings to facilitate the return of injured athletes to competition, despite a lack of high-quality evidence. Given the possibility cryotherapy may increase the risk of injury, by reducing nerve conduction velocity, muscle force production, and proprioceptive afferent information, further research is needed to evaluate its effects on proprioception, particularly in the shoulder joint, which has the greatest range of motion of any joint in the body, where there is a dearth of studies.

Methods: We conducted a pre-registered, 1:1 block randomized, baseline controlled, double blind (outcome assessor and statistician), crossover trial of cryotherapy without compression and cryotherapy with compression.

Distributed network of optically pumped magnetometers for space weather monitoring.

Spatial variation in the intensity of magnetospheric and ionospheric fluctuations during solar storms creates ground-induced currents, of importance in both infrastructure engineering and geophysical science. This activity is presently measured using a network of ground-based magnetometers, typically consisting of extensive installations at established observatory sites. We show that this network can be enhanced by the addition of remote quantum magnetometers which combine high sensitivity with intrinsic calibration.

A cynomolgus monkey urinary tract infection model confirms efficacy of new FimH vaccine candidates.

The increase in urinary tract infections (UTI) caused by antibiotic-resistant requires the development of new therapeutic agents and prophylactic vaccines. To evaluate the efficacy of new lead candidates, we implemented a cynomolgus macaque UTI challenge model that mimics human uncomplicated cystitis in response to transurethral challenge with a multidrug-resistant (MDR) serotype O25b ST131 isolate. fimbrial adhesin FimH and O-antigens are separately under clinical evaluation by others as vaccine candidates to prevent UTI and invasive urosepsis disease, respectively.

Actively tunable laser action in GeSn nanomechanical oscillators.

Mechanical forces induced by high-speed oscillations provide an elegant way to dynamically alter the fundamental properties of materials such as refractive index, absorption coefficient and gain dynamics. Although the precise control of mechanical oscillation has been well developed in the past decades, the notion of dynamic mechanical forces has not been harnessed for developing tunable lasers. Here we demonstrate actively tunable mid-infrared laser action in group-IV nanomechanical oscillators with a compact form factor.