Comprehensive untargeted polar metabolite analysis using solvent switching liquid chromatography tandem mass spectrometry.

Metabolomics analyses enable the examination and identification of endogenous biochemical reaction products, revealing information on the metabolic pathways and processes active within a living cell or organism. Determination of metabolic shifts can provide important information on a treatment or disease. Unlike other omics fields that typically have analytes of the same chemical class with common building blocks, those that fall under the nomenclature of metabolites encompass a wide array of different compounds with very diverse physiochemical properties.

Evaluation of combined workflows for multimodal mass spectrometry imaging of elements and lipids from the same tissue section.

The wide range of mass spectrometry imaging (MSI) technologies enables the spatial distributions of many analyte classes to be investigated. However, as each approach is best suited to certain analytes, combinations of different MSI techniques are increasingly being explored to obtain more chemical information from a sample. In many cases, performing a sequential analysis of the same tissue section is ideal to enable a direct correlation of multimodal data.

Learning everyday multitasking activities-An online survey about people's experiences and opinions.

Multitasking (MT)-performing more than one task at a time-has become ubiquitous in everyday life. Understanding of how MT is learned could enable optimizing learning regimes for tasks and occupations that necessitate frequent MT. Previous research has distinguished between MT learning regimes in which all tasks are learned in parallel, single-task (ST) learning regimes in which all tasks are learned individually, and mixed learning regimes (Mix) in which MT and ST regimes are mixed.