Publications by authors named "D Vizcarra"
Article Synopsis
- The study focuses on improving cryopreservation techniques for ovarian tissue by examining the influence of factors like corpus luteum presence and the side of the ovaries on cell viability and morphology.
- The researchers categorized bovine ovaries into six groups based on whether they had a corpus luteum and their side (right or left), finding that ovaries without a corpus luteum and from the right side showed the best tissue preservation.
- Findings indicate that recognizing the origin of the ovarian samples can enhance the success of ovarian tissue vitrification, suggesting a new approach for better outcomes in cryopreservation.
Practical issues concerning the use of Magnetic Resonance Imaging in Multiple Sclerosis in Latin America: Discussion from 16 centres on behalf of the Foro Latam EM Study Group.
Ethel Ciampi Carolina Guerra-Posada Irene Treviño-Frenk Fernando Cortes-Enriquez Edgar Patricio Correa-Díaz Darwin Vizcarra
Mult Scler Relat Disord
March 2022
Article Synopsis
- Recent MAGNIMS-CMSC-NAIMS recommendations on MRI use in multiple sclerosis (MS) have been crucial for enhancing patient treatment.
- Implementation of these guidelines is inconsistent across various countries, indicating the need to tackle local challenges.
- A group of 14 MS neurologists from 16 centers in Latin America convened to evaluate MRI access, standardization of protocols, and opportunities for collaborative research in MS.
As human and economic resources are limited, especially in Latin America (LATAM), it is important to identify research priorities to improve multiple sclerosis (MS) patients care in the region. The objective was to generate a multidisciplinary consensus on research priorities in MS for patients care in LATAM by involving healthcare professionals and MS patient associations. METHODS: consensus was reached through a four-step modified Delphi method designed to identify and rate research priorities in MS in LATAM.
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- The study investigates how different synthetic polymers (Supercool X-1000, Supercool Z-1000, and PVP K-12) affect the vitrification process of bovine ovarian tissue, which is critical for successful preservation.
- Results showed that ovarian tissue treated with Supercool X-1000 had the highest percentage of morphologically normal follicles and stronger AQP9 labeling post-thawing than other treatments.
- However, the PVP K-12 group showed less degeneration and tissue damage, with ROS levels similar to fresh controls, suggesting that a combination of X-1000 and PVP K-12 could enhance outcomes for vitrified ovarian tissues.