Publications by authors named "D Vinereanu"
: Systemic sclerosis (SSc) causes myocardial and microvascular impairment, with subclinical dysfunction and eventually permanent cardio-vascular damage. The long-term influence of SSc therapies on subclinical cardiovascular dysfunction is insufficiently investigated. We aimed to assess 2D and 4D cardiac ultrasound parameters of heart function in patients with different forms of SSc versus controls and to determine the evolution of cardiac function and arterial stiffness parameters under therapy.
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- The EuroHeart project aims to establish standardized definitions for outcome measures in cardiovascular clinical studies to enhance the evaluation of medical interventions and care.
- A group of 82 experts formed five Working Groups to identify key outcome measures for various cardiovascular conditions, using a systematic review and consensus methods to define these measures.
- In total, 24 mandatory (Level 1) and 48 optional (Level 2) outcome measures were established across five cardiovascular disease areas, providing a foundation for improved research and patient care quality.
Article Synopsis
- * Current guidelines emphasize that lower levels of low-density lipoprotein cholesterol (LDL-C) are better, advocating for early and aggressive treatment, including a variety of effective medications beyond just statins.
- * The International Lipid Expert Panel (ILEP) has published guidelines for optimizing LLT in post-ACS patients, highlighting the need for combination therapies and personalized care to improve adherence and treatment outcomes among high-risk individuals.
Article Synopsis
- * A working group, including experts from the European Society of Cardiology, conducted a systematic review and reached consensus on mandatory (Level 1) and optional (Level 2) measures through a Delphi process.
- * The final catalogue includes five Level 1 and two Level 2 outcome measures, along with five additional monitoring outcomes, which will enhance research quality and improve heart failure care.
Article Synopsis
- * A retrospective study in Romania analyzed 198 patients with venous thromboembolic disease, comparing those with (Group 1) and without (Group 2) COVID-19 during the pandemic's early waves.
- * Results showed Group 1 had worse clinical markers, longer ICU stays, and a trend towards higher mortality, while the PESI score was only predictive of death in patients without COVID-19.