Patterns of Congenital Syphilis in a Large Public Hospital: Birthing Parent Risk Factors and Infant Outcomes.

Background: Congenital syphilis (CS) in the United States increased 10-fold in the last decade. At a large public hospital in Los Angeles, the numbers of infants born to birthing parents with untreated syphilis during pregnancy have continued to rise.

Methods: We compiled a retrospective case-series from all infant rapid plasma reagin (RPR) test results from 2022-2023 summarizing CS diagnosis and relevant diagnostic criteria.

Expanding Horizons in Syphilis Treatment: Challenges, Advances, and Opportunities for Alternative Antibiotics.

Purpose Of Review: This review examines the growing need for alternative technologies to address the resurgence of syphilis, particularly its congenital and late-stage manifestations. It explores current treatment paradigms, highlights the limitations of penicillin, and evaluates emerging evidence on new therapies and diagnostics to inform future strategies.

Recent Findings: Recent breakthroughs in Treponema pallidum culture techniques have enabled antibiotic susceptibility testing, expanding knowledge on both established and emerging treatment options.

Effect of Feeding Environmental Enrichment on Lesser Anteaters' Behavior, Space Use and Food Selectivity.

Studying behavioral response to management and housing conditions provides specific evidence to enhance animal welfare. Feeding environmental enrichment (FEE) is a powerful strategy to meet welfare challenges. Lesser anteaters' ;  = 7) response to FEE was assessed by analyzing behavior and space use through focal sampling every 5 minutes/24 hours using cameras.

Spatially Localized Visual Perception Estimation by Means of Prosthetic Vision Simulation.

Retinal prosthetic devices aim to repair some vision in visually impaired patients by electrically stimulating neural cells in the visual system. Although there have been several notable advancements in the creation of electrically stimulated small dot-like perceptions, a deeper comprehension of the physical properties of phosphenes is still necessary. This study analyzes the influence of two independent electrode array topologies to achieve single-localized stimulation while the retina is electrically stimulated: a two-dimensional (2D) hexagon-shaped array reported in clinical studies and a patented three-dimensional (3D) linear electrode carrier.

Identifying and Removing Fraudulent Attempts to Enroll in a Human Health Improvement Intervention Trial in Rural Communities.

Using the internet to recruit participants into research trials is effective but can attract high numbers of fraudulent attempts, particularly via social media. We drew upon the previous literature to rigorously identify and remove fraudulent attempts when recruiting rural residents into a community-based health improvement intervention trial. Our objectives herein were to describe our dynamic process for identifying fraudulent attempts, quantify the fraudulent attempts identified by each action, and make recommendations for minimizing fraudulent responses.