Publications by authors named "D Vijaykrishna"
Diverse paramyxoviruses have coevolved with their bat hosts, including fruit bats such as flying foxes (Chiroptera: Pteropodidae). Several of these viruses are zoonotic, but the diversity and distribution of are poorly understood. We screened pooled feces samples from three colonies and assayed tissues, rectal swabs, and oral swabs from 95 individuals of 23 pteropodid species sampled at 17 sites across the Indonesian archipelago with a conventional paramyxovirus PCR; all tested negative.
View Article and Find Full Text PDFArticle Synopsis
- Australian avian influenza A viruses (AIVs) are distinct from those in Eurasia and the Americas, indicating the presence of endemic strains influenced by sporadic introductions.
- A five-year study showed low AIV prevalence in ruddy turnstones during the Austral summer, but a surprising spike to 32% prevalence was found in an isolated population in March 2014.
- The study revealed diverse AIV genotypes, highlighting the circulation and genetic reassortment of viruses in Australian wild birds, emphasizing the need for long-term surveillance to understand AIV dynamics in regions with limited migrant birds.
During March 2017, a neonatal patient with severe diarrhoea subsequently developed septicaemia and died, with isolated as the causative microorganism. In keeping with infection control protocols, the coincident illness of an attending staff member and three other neonates with infection triggered an outbreak response, leading to microbiological assessment of isolates collected from the staff member and all 21 co-housed neonates. Multilocus sequence typing and genomic sequencing identified that the isolates from the 21 neonates were of a new sequence type, ST2727, and taxonomically belonged to subsp.
View Article and Find Full Text PDFT cell recognition of peptides presented by human leukocyte antigens (HLAs) is mediated by the highly variable T cell receptor (TCR). Despite this built-in TCR variability, individuals can mount immune responses against viral epitopes by using identical or highly related TCRs expressed on CD8 T cells. Characterization of these TCRs has extended our understanding of the molecular mechanisms that govern the recognition of peptide-HLA.
View Article and Find Full Text PDFEpidemiological trends in notified influenza cases in Australia's Northern Territory, 2007-2016.
Influenza Other Respir Viruses
September 2020
Background: The Northern Territory (NT) of Australia has a mix of climates, sparsely distributed population and a large proportion of the populace are Indigenous Australians, and influenza is known to have a disproportionate impact upon this group. Understanding the epidemiology of influenza in this region would inform public health strategies.
Objectives: To assess if there are consistent patterns in characteristics of influenza outbreaks in the NT.