Publications by authors named "D Vignes"

Objectives: High-flow nasal cannula (HFNC) was widely used during the COVID-19 pandemic in intensive care units (ICU), but there is no recommendation for elderly patients non-eligible for ICU management. We aimed to describe the outcomes of HFNC treatment in patients with COVID-19 who are not eligible for ICU management.

Methods: Retrospective bicentric cohort study performed between September 1, 2020 and June 30, 2021 in two infectious diseases departments of Colmar Hospital and Antoine Beclere University Hospital, France.

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Background: Beyond sex, age, and various comorbidities, geographical origin and socioeconomic deprivation are associated with Coronavirus Disease (COVID-19) morbidity and mortality in the general population. We aimed to assess factors associated with severe forms of COVID-19 after a hospital emergency department visit, focusing on socioeconomic factors.

Methods: Patients with laboratory-confirmed COVID-19 attending the emergency department of Béclère Hospital (France) in March-April 2020 were included.

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Article Synopsis
  • This study explored how various socioclinical, inflammatory, and metabolic factors are linked to weight gain in HIV patients on combination antiretroviral therapy (cART).
  • Researchers analyzed data from individuals who were normal weight at the start of cART and maintained virological suppression for 36 months, looking at factors like BMI, inflammation markers, and socioeconomic status.
  • They found that 20% of participants became overweight or obese after 36 months, with factors such as higher initial BMI, being from sub-Saharan Africa, and certain inflammatory markers influencing this weight gain.
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