Fibroin-Hybrid Systems: Current Advances in Biomedical Applications.

Fibroin, a protein extracted from silk, offers advantageous properties such as non-immunogenicity, biocompatibility, and ease of surface modification, which have been widely utilized for a variety of biomedical applications. However, in vivo studies have revealed critical challenges, including rapid enzymatic degradation and limited stability. To widen the scope of this natural biomacromolecule, the grafting of polymers onto the protein surface has been advanced as a platform to enhance protein stability and develop smart conjugates.

Use of multispecies (Nannochloropsis oceanica, Artemia franciscana, and Arbacia nigra) approach to assess the quality of marine water from Callao Bay, Peru.

Multi-species tests in bioassays offer a holistic view of the ecosystem's response to toxicity, as different species display varying sensitivities to pollutants. This research aimed to assess the ability of toxicity tests' to distinguish contamination levels, examine site-specific effects, and investigate seasonal variability. Using a multispecies approach (Nannochloropsis oceanica, Artemia franciscana, and Arbacia nigra), bioassays evaluated marine water quality from Callao Bay in Peru across four sampling areas (Naval School: PA1, Peruvian Marine Institute: PA2, Callao Pier: PA3, and San Lorenzo Island: PA4).

First report of as a causal agent of post-harvest disease of watermelons () in Brazil.

Watermelon (), it's an important fruit in Brazil, producing 1.9 million ton/year, occupies the fifth place in the world, (FAO, 2022), but post-harvest diseases are a major limitation, leading to losses of up to 15% (Balasubramaniam et al. 2023).

Responders COPD patients to two different home-based rehabilitation programs: a blind, randomized, and controlled clinical trial.

Purpose: To verify the number of patients with COPD responders to two different home-based rehabilitation programs.

Methods: This was a blinded, randomized, and controlled clinical trial. The six-minute step test (6MST), one-minute sit-stand test (1-MSTST), six-minute walk test (6MWT), COPD Assessment Test (CAT), modified Medical Research Council (mMRC), monitoring of physical activity in daily life, and isometric quadriceps muscle strength were assessed pre- and post-intervention.