Publications by authors named "D Verver"

Article Synopsis
  • The study focuses on stage I and II melanoma survivors to understand their experiences and survivorship care needs after treatment, highlighting the lack of research in this area despite the rising incidence of localized melanoma.
  • The qualitative research involved 18 survivors divided into focus groups, revealing that they experienced significant emotional and physical challenges after treatment, alongside a mix of relief and fear as they navigated life post-diagnosis.
  • Survivors emphasized the need for tailored information, accessible resources, and ongoing, patient-centered support to help them adjust and improve their quality of life after melanoma treatment.
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Article Synopsis
  • Previous studies indicate that vacuum-assisted excision (VAE) is a safe alternative to surgical excision (SE) for benign breast lesions, although its use for high-risk lesions is still debated and lacks clear guidelines.
  • This study compared two groups of patients, one treated before the introduction of VAE and the other after, analyzing excision, complication, and recurrence rates.
  • Results showed that VAE was increasingly used for benign lesions, with comparable low rates of re-excision, recurrence, and complications, suggesting a significant potential to replace SE in many cases while reducing the need for surgery and anesthesia.
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Background: The current standard of care for patients without sentinel node (SN) metastasis (i.e., stage I−II melanoma) is watchful waiting, while >40% of patients with stage IB−IIC will eventually present with disease recurrence or die as a result of melanoma.

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Talimogene laherparepvec (T-VEC) is an intralesional oncolytic virotherapy for patients with irresectable stage III-IVM1a cutaneous melanoma. Although this treatment is considered to mainly act through T cell-mediated mechanisms, prominent numbers of plasma cells after T-VEC treatment have been described. The aim was to investigate how often these plasma cells were present, whether they were relevant in the response to treatment, and if these or other histopathological features were associated with durable response to treatment.

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