Publications by authors named "D Verrot"
Importance: Evidence for the long-term efficacy and safety of anti-tumor necrosis factor α agents (anti-TNF) in treating cutaneous sarcoidosis is lacking.
Objective: To determine the efficacy and safety of anti-TNF in treating cutaneous sarcoidosis in a large observational study.
Design, Setting, And Participants: STAT (Sarcoidosis Treated with Anti-TNF) is a French retrospective and prospective multicenter observational database that receives data from teaching hospitals and referral centers, as well as several pneumology, dermatology, and internal medicine departments.
Objectives: Type 1 Gaucher disease may be related to the presence of autoantibodies. Their clinical significance is questioned. Primary endpoint was to compare the prevalence of autoantibodies in type 1 Gaucher disease patients with healthy subjects, seeking correlations with autoimmune characteristics.
View Article and Find Full Text PDFWe describe a case of fatal fulminant hepatitis E concomitant to malignant B cell lymphoma in a 73-year-old French woman. Infection was with an autochthonous hepatitis E virus of genotype 3f. Frequent consumption of uncooked pig liver sausage (figatellu) was the only risk factor found.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates gene mutations in non-chronic myeloid leukemia (CML) myeloproliferative neoplasms (MPNs), focusing on three classic subtypes: polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF).
- JAK2 was consistently mutated across all MPN types, with 100% in PV, 66% in ET, and 68% in MF, highlighting its significance in these conditions.
- High rates of ASXL1 mutations were observed specifically in MF patients (20%), while mutations in other genes like CBL, DNMT3A, and others were rare or absent in the MPN cohort studied.