The Isolation and Assessment of the Levels of Microbial Pathogens From Saliva, Hands, and Currency Notes.

Introduction Currencies such as coins and paper notes are always used for the purchase of products and services by the common man. These currencies are constantly being subjected to contamination and thus serve as a potential medium for the transfer of microbial pathogens. Thus, this study aims to establish public awareness of the proper handling of currency notes to prevent cross-contamination and the incidence of infectious diseases.

Synergistic Action of Rutin-Coated Zinc Oxide Nanoparticles: Targeting Biofilm Formation Receptors of Dental Pathogens and Modulating Apoptosis Genes for Enhanced Oral Anticancer Activity.

Oral diseases are often associated with bacterial and fungal pathogens such as Staphylococcus aureus, Streptococcus mutans, Enterococcus faecalis, and Candida albicans. This research explored a novel approach to addressing these pathogens by synthesizing zinc oxide nanoparticles (ZnO NPs) coated with rutin (RT), a plant-derived compound. The synthesized ZnO-RT NPs were comprehensively characterized using UV-Vis spectrophotometer, SEM, and EDAX techniques to confirm their structural composition.

Splenic Dysfunction in Children With Sickle Cell Disease: A Single Centre Experience From Central India.

Objective: To assess the prevalence and predictors of splenic dysfunction in children with sickle cell disease (SCD).

Methods: A cross-sectional study was conducted between June 2019 and December 2020 where children aged 1 to 15 years of age with SCD were screened for splenic dysfunction. Children who were splenectomised, those with other diseases known to affect splenic function like congenital malformations, immunodeficiencies, and chronic diseases like tuberculosis, nephrotic syndrome, diabetes mellitus, chronic liver disease, celiac disease or malignancy were excluded.

Systems approach to design multi-epitopic peptide vaccine candidate against fowl adenovirus structural proteins for .

Introduction: Fowl adenovirus (FAdV) is a significant pathogen in poultry, causing various diseases such as hepatitis-hydropericardium, inclusion body hepatitis, and gizzard erosion. Different serotypes of FAdV are associated with specific conditions, highlighting the need for targeted prevention strategies. Given the rising prevalence of FAdV-related diseases globally, effective vaccination and biosecurity measures are crucial.