Publications by authors named "D V Woo"
Article Synopsis
- The study analyzed preoperative data from adult spinal deformity patients to establish a threshold for T1 slope (T1S) from cervical radiographs that indicates thoracolumbar malalignment.
- Researchers found a specific cutoff of 30 degrees for high T1S, with 50% of the patients falling above this threshold.
- Notably, higher T1S was linked with greater thoracic kyphosis, sagittal vertical axis, T1-pelvic angle, and pelvic tilt, suggesting that this measurement could serve as a useful parameter in cervical evaluations.
Cannabinoids interact with cannabinoid receptors, influencing diverse central nervous system (CNS) and peripheral functions, including anxiety, depression, and cognition. CB1 and CB2 receptors modulate signaling cascades via G-protein coupling, with anandamide acting as an endogenous ligand for CB1 receptors. LY-2183240, a putative endocannabinoid transport blocker, elevates brain anandamide levels, showing therapeutic potential in pain management and alcohol-related behaviors.
View Article and Find Full Text PDFl-3,4-Dihydroxyphenylalanine (levodopa and L-DOPA in this text), alongside dopamine, boasts high biocompatibility, prompting industrial demand for its use as a coating material. Indeed, the effectiveness of L-DOPA is steadily rising as it serves as an oral therapeutic agent for neurodegenerative brain diseases, particularly Parkinson's disease (PD). However, the effects of L-DOPA on the growth and function of astrocytes, the main glial cells, and the most numerous glial cells in the brain, are unknown.
View Article and Find Full Text PDFArticle Synopsis
- - The study analyzed individual patient data from multiple trials to assess sex-specific differences in clinical characteristics and outcomes of patients with spontaneous intracerebral hemorrhage (ICH).
- - Results showed that while males were younger and had larger brain bleeds and a higher risk of bleed expansion compared to females, they also had a lower risk of poor functional outcomes.
- - The findings indicate distinct biological and clinical pathways in males and females with ICH, emphasizing the need for targeted research based on sex differences in this condition.