Strengthening exercises improve symptoms and quality of life but do not change autonomic modulation in fibromyalgia: a randomized clinical trial.

Objective: Autonomic dysfunction is an important mechanism that could explain many symptoms observed in fibromyalgia (FM). Exercise is an effective treatment, with benefits potentially mediated through changes in autonomic modulation. Strengthening is one of the less studied exercises in FM, and the acute and chronic effects of strengthening on the autonomic system remain unknown.

Myocardial remodeling after large infarcts in rat converts post rest-potentiation in force decay.

Background: Post-rest contraction (PRC) of cardiac muscle provides indirect information about the intracellular calcium handling.

Objective: Our aim was to study the behavior of PRC, and its underlying mechanisms, in rats with myocardial infarction.

Methods: Six weeks after coronary occlusion, the contractility of papillary muscles (PM) obtained from sham-operated (C, n=17), moderate infarcted (MMI, n=10) and large infarcted (LMI, n=14) rats was evaluated, following rest intervals of 10 to 60 seconds before and after incubation with lithium chloride (Li(+)) substituting sodium chloride or ryanodine (Ry).

Altered cardiovascular reactivity to mental stress but not to cold pressure test in migraine.

Objectives: This study assessed cardiovascular reactivity to mental stress and cold pressure test in migraineurs and controls. It compared the cardiovascular reactivity between patients with migraine with aura and patients with migraine without aura.

Background: Several studies have assessed the autonomic nervous system functioning and cardiovascular responses to stressor stimuli in migraine.