[Antioxidant efficacy in the treatment of cardiac metabolism disorders during endotoxicosis].

Chronic experiments on dogs showed that antioxidant drugs (reamberin, ximedone, vitamin E) are highly effective in correcting the functional and metabolic disorders in myocardium under endogenous intoxication conditions. Recovery of the functional activity was accompanied by correction of the lipid metabolism of cardiac cell structures. One mechanism of the drug action is related to a decrease in the lipid peroxidation rate and phospholipase A2 activity in cardiac tissue structures.

Dynamics of interstimulus intervals in the activity of neurons of the sensorimotor cortex during the development of a food-procuring reflex in the rabbit.

The impulse activity of neurons of the sensorimotor cortex (SMC) during the formation of a food-procuring reflex in the rabbit, as well as in trained animals if reinforcement is discontinued and substituted, was investigated. In the process of training the neurons of the SMC acquire the capacity for anticipatory reactions. The sudden abolition and substitution of reinforcement elicits the appearance of activity which is characteristic for the process of discordance in the acceptor of the result of the action.

[The dynamics of the interimpulse intervals in the activity of sensorimotor cortex neurons during the acquisition of the food-procuring reflex in the rabbit].

State of hunger is characterized by the presence of definite distribution of interimpulse intervals in the activity of sensorimotor cortical neurones (SMC) of rabbit. Mostly bi- and three-modal distribution of interimpulse intervals in the background activity in hungry animals changes in the process of elaboration of food-procuring habit. As the habit consolidates, the SMC neurones acquire the ability to forestalling actions.