Stimulatory effect of volatile urinary components from intact mice on the proliferative activity of splenic lymphoid tissue in irradiated animals.

Immunohistochemical and morphometric analyses have demonstrated long-distance stimulatory effects of the natural volatile components of the urine of intact mice on the proliferation of splenic lymphocytes in mice exposed to a single total γ-irradiation in a dose of 1 Gy. These results are in line with the data on stimulation of the humoral immune response to thymus-dependent antigen in irradiated mice exposed to urine specimens of intact animals.

[Influence of ionizing radiation on the attractiveness of male mice to chemosignals of intact individuals].

Within short-terms after exposure to ionizing radiation, CBA and C57Bl/6 male mice were found not only to retain but also to enhance their attractiveness to chemosignals of intact males of the same genotype (syngenic). It was shown that the time period of higher attractiveness increased with the absorbed dose (from 1 to 6 Gy). Within several days after exposure to 6-Gy irradiation, male mice were temporarily unable to discriminate between chemosignals of syngenic and allogenic (alien genotype) individuals.

[Influence of the irradiating on olfactory ability of male mice to distinguish chemo-signals of intact individuals].

It is shown, that in early terms after irradiating of male mice of lines CBA and C57Bl/6 in a sublethal dose (4 Gy) in reaction of preference-avoiding lose olfactory ability to distinguish the genotype of flying secretions of female mice and to distinguish flying secretions of female mice from secretions of male mice. Irradiated male mice not only preserve, but also raise the attractiveness to chemosignals of syngenetic intact male mice.